Results 21 to 30 of about 1,671,076 (389)

Reviewer bias in single- versus double-blind peer review

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Significance Scientific peer review has been a cornerstone of the scientific method since the 1600s. Debate continues regarding the merits of single-blind review, in which anonymous reviewers know the authors of a paper and their affiliations, compared ...
Andrew Tomkins, M. Zhang, W. Heavlin
semanticscholar   +1 more source

Effectiveness and Safety of Heparinized Saline versus Normal Saline in Maintaining Patency of Peripheral Intravenous Locks in Neonates at a Tertiary Care Hospital [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Heparinized saline is usually used as a regular flush solution to prevent occlusion of peripheral intravenous locks in neonates but the risks associated with the use of heparin cannot be ignored in these patients.
Treasa Mathews   +7 more
doaj   +1 more source

Blinded assessment of treatment effects utilizing information about the randomization block length [PDF]

open access: yes, 2009
It is essential for the integrity of double-blind clinical trials that during the study course the individual treatment allocations of the patients as well as the treatment effect remain unknown to any involved person.
Barbui   +18 more
core   +1 more source

Supraclavicular brachial plexus block: Comparison of varying doses of dexmedetomidine combined with levobupivacaine: A double-blind randomised trial

open access: yesIndian Journal of Anaesthesia, 2017
Background and Aims: The ideal dose of dexmedetomidine for brachial plexus block is a matter of debate. This study was carried out to evaluate 50 μg or 100 μg of dexmedetomidine added to 0.5% levobupivacaine, with regard to the duration of analgesia. Our
Srinivasa Rao Nallam   +2 more
doaj   +1 more source

A meta-analysis of pharmacotherapy for social anxiety disorder: an examination of efficacy, moderators, and mediators [PDF]

open access: yes, 2017
INTRODUCTION: Social anxiety disorder (SAD) is among the most prevalent mental disorders, associated with impaired functioning and poor quality of life. Pharmacotherapy is the most widely utilized treatment option.
Borenstein M   +8 more
core   +2 more sources

Multicenter, Double-Blinded, Randomized, Active-Sham Controlled Clinical Study Design to Assess the Safety and Effectiveness of a Novel High Frequency Electric Nerve Block System in the Treatment of Post-Amputation Pain (The QUEST Study)

open access: yesJournal of Pain Research, 2022
Leonardo Kapural,1 Nemath Syed Shah,2 Zi-Ping Fang,2 Nagy Mekhail3 1Carolinas Pain Institute, Winston-Salem, NC, USA; 2Neuros Medical, Inc., Willoughby Hills, OH, USA; 3Evidence-Based Pain Management Research, Department of Pain Management, Cleveland ...
Kapural L   +3 more
doaj  

Antibiotics for sore throat [PDF]

open access: yes, 2013
Background: Sore throat is a common reason for people to present for medical care. Although it remits spontaneously, primary care doctors commonly prescribe antibiotics for it.
Del Mar, Chris B.   +2 more
core   +1 more source

How to maintain the maximal level of blinding in randomisation for a placebo-controlled drug trial

open access: yesContemporary Clinical Trials Communications, 2019
We illustrate the approach of randomising treatments and compare it with the traditional approach of randomising patients, using a case study drawn from the authors’ experience in clinical trials. The setting is a double-blind parallel two-arm randomised
Lei Clifton, David A. Clifton
doaj   +1 more source

Fluphenazine decanoate (depot) and enanthate for schizophrenia [PDF]

open access: yes, 2015
Background: Intramuscular injections (depot preparations) offer an advantage over oral medication for treating schizophrenia by reducing poor compliance.
Abuzzahab   +336 more
core   +1 more source

Caffeine supplementation improves countermovement jump in youth soccer players: a pilot study

open access: yesRevista Española de Nutrición Humana y Dietética, 2017
Introduction: The objective of this study was to analyze the effect of caffeine ingestion in soccer performance, particularly in the countermovement jump test (CMJ).
Juan Diego Hernández-Camacho   +3 more
doaj   +1 more source

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