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Prospective, Double-Blind Evaluation of Umbilicoplasty Techniques Using Conventional and Crowdsourcing Methods

Plastic & Reconstructive Surgery, 2017
Background: Umbilical reconstruction is an important component of deep inferior epigastric perforator (DIEP) flap breast reconstruction. This study evaluated the aesthetics of three different umbilical reconstruction techniques during DIEP flap breast reconstruction.
Veldhuisen, C.L. Van   +9 more
openaire   +4 more sources

Tapping-in Method (Skin Penetration Technique) with a Placebo Needle for Double-Blind Acupuncture Trials

The Journal of Alternative and Complementary Medicine, 2013
This study investigated the effect of acupuncture needles developed for double-blind (practitioner-patient blinding) trials employing a tapping-in method that is commonly used to penetrate the skin in Japanese-style acupuncture. DESIGN, SUBJECTS, AND INTERVENTIONS: An acupuncturist applied a penetrating, a skin-touch placebo, and a no-touch control ...
Miho Takayama   +3 more
openaire   +5 more sources

Lurasidone monotherapy in the treatment of bipolar I depression: a randomized, double-blind, placebo-controlled study.

American Journal of Psychiatry, 2014
OBJECTIVE The authors evaluated the efficacy and safety of lurasidone in the treatment of patients with major depressive episodes associated with bipolar I disorder.
A. Loebel   +6 more
semanticscholar   +1 more source

Lurasidone as adjunctive therapy with lithium or valproate for the treatment of bipolar I depression: a randomized, double-blind, placebo-controlled study.

American Journal of Psychiatry, 2014
OBJECTIVE Few studies have been reported that support the efficacy of adjunctive therapy for patients with bipolar I depression who have had an insufficient response to monotherapy with mood-stabilizing agents.
A. Loebel   +6 more
semanticscholar   +1 more source

Add-on treatment of benzoate for schizophrenia: a randomized, double-blind, placebo-controlled trial of D-amino acid oxidase inhibitor.

JAMA psychiatry, 2013
IMPORTANCE In addition to dopaminergic hyperactivity, hypofunction of the N-methyl-d-aspartate receptor (NMDAR) has an important role in the pathophysiology of schizophrenia.
H. Lane   +8 more
semanticscholar   +1 more source

Evaluation of phenazocine with meperidine as an analgesic agent during labor, by the double blind method

American Journal of Obstetrics and Gynecology, 1964
Abstract 1. 1. A new synthetic narcotic, phenazocine, was compared to meperidine as an analgesic agent during labor by double blind method involving a total of 194 unselected obstetrical patients on the obstetrics service at Walter Reed General Hospital. One half of the patients received the control and the remainder, the test drug. Evaluation of
H.L. Riva, Robert O. Olson
openaire   +3 more sources

Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia.

American Journal of Psychiatry, 2000
OBJECTIVE Since all antipsychotics block dopamine D(2) receptors, the authors investigated how well D(2) receptor occupancy in vivo predicts clinical response, extrapyramidal side effects, and hyperprolactinemia.
S. Kapur   +5 more
semanticscholar   +1 more source

Lurasidone in the treatment of schizophrenia: a randomized, double-blind, placebo- and olanzapine-controlled study.

American Journal of Psychiatry, 2011
OBJECTIVE The study was designed to evaluate the short-term efficacy and safety of lurasidone in the treatment of acute schizophrenia. METHOD Participants, who were recently admitted inpatients with schizophrenia with an acute exacerbation of psychotic
H. Meltzer   +9 more
semanticscholar   +1 more source

A randomized, double-blind, placebo-controlled study of light therapy for antepartum depression.

Journal of Clinical Psychiatry, 2011
OBJECTIVE Affective disorder during pregnancy is a common condition requiring careful judgment to treat the depression while minimizing risk to the fetus. Following up on promising pilot trials, we studied the efficacy of light therapy.
A. Wirz-Justice   +11 more
semanticscholar   +1 more source

A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia.

Journal of Clinical Psychiatry, 2010
BACKGROUND Current antipsychotics have only a limited effect on 2 core aspects of schizophrenia: negative symptoms and cognitive deficits. Minocycline is a second-generation tetracycline that has a beneficial effect in various neurologic disorders ...
Y. Levkovitz   +8 more
semanticscholar   +1 more source

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