Results 61 to 70 of about 1,671,076 (389)

The Effect of Nopalea™, a Nutritional Supplement Containing Cactus Fruit Juice, on C-Reactive Protein Levels in Healthy Adults Assessed using a Randomized, Double-Blind, and Controlled Experimental Design [PDF]

, 2014
This study was developed to investigate the anti-inflammatory effects of a commercial product (Nopalea™) containing Prickly Pear Cactus Fruit Juice in 286 healthy adults.
Diefenbach, Patricia, Mattie, Mark, Patel, Sarwat, Schmeck, Cynthia, Tsnobiladze, Medeya   +4 more
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Adjunctive brexpiprazole in patients with major depressive disorder and anxiety symptoms: post hoc analyses of three placebo-controlled studies

Neuropsychiatric Disease and Treatment, 2018
Michael E Thase,1 Emmanuelle Weiller,2 Peter Zhang,3 Catherine Weiss,4 Roger S McIntyre5 1Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania and the Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, USA ...
Thase ME, Weiller E, Zhang P, Weiss C, McIntyre RS   +4 more
doaj  

Double regularization medical CT image blind restoration reconstruction based on proximal alternating direction method of multipliers

EURASIP Journal on Image and Video Processing, 2017
To solve the problem of CT image degradation, a double regularization CT image blind restoration reconstruction method was proposed. The objective function including both a clear image and point spread function was established.
Jingyu Zhang, Yunshan Sun, Yuan Zhang, Jianfu Teng   +3 more
doaj   +1 more source

CoQ10 and vitamin A supplementation support voice rehabilitation. A double-blind, randomized, controlled, three-period cross-over pilot study [PDF]

, 2019
Objectives: To evaluate the effectiveness of an adjuvant therapy (CoQ10 in its watersoluble form and vitamin A) in supporting voice rehabilitation in a large group of patients with muscle tension dysphonia (MTD).
de Vincentiis, M, Flaccadoro, F, Greco, A, Longo, L, Mancini, P, Mango, C, Nicastri, M, PESCERELLI, Patrizia, Ruoppolo, G   +8 more
core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Cognitive tests used in chronic adult human randomised controlled trial micronutrient and phytochemical intervention studies [PDF]

, 2010
In recent years there has been a rapid growth of interest in exploring the relationship between nutritional therapies and the maintenance of cognitive function in adulthood.
Anderson, Anna L. Macready, Balk, Burgess, Claire M. Williams, Clarke, Detterman, Eussen, Fournier, Ho, Ivers, Jeremy P. E. Spencer, Judi A. Ellis, Knapp, Laurie T. Butler, Lezak, Manly, Maylor, McDaniel, Orla B. Kennedy, Phillips, Rabbitt, Reitan, Rosen, Rugg, Santos, Wechsler, Wechsler, Wesnes   +28 more
core   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

The role of pudendal nerve block in hemorrhoid surgery: a systematic review and meta-analysis of double-blind randomized controlled trials

Frontiers in Medicine, 2023
BackgroundPudendal nerve block (PNB) is a commonly used anesthesia method that has been widely used in postoperative analgesia for hemorrhoids in recent years.
Shijun Xia, Lidan Luo, Wenjiang Wu, Kaiyuan Lu, Tao Jiang, Yue Li   +5 more
doaj   +1 more source

Pain relief for women with cervical intraepithelial neoplasia undergoing colposcopy treatment [PDF]

, 2012
Treatment for CIN is usually undertaken in an outpatient colposcopy clinic to remove the pre-cancerous cells from the cervix. It commonly involves lifting the cells off the cervix with electrically heated wire (diathermy) or laser, or destroying the ...
AI-Kurdi, Anthony, Connell, Crompton, Cruickshank, Deeks, DerSimonian, Diakomanolis, Duncan, Frega, Higgins, Howells, Huskisson, Johnson, Johnston, Jordan, Lee, Lipscomb, Lowles, Martin-Hirsch, Melzack, Mikhail, Moore, Peto, Rogstad, Sammarco, Sant, Sarkar, Sharp, Spielberger, Winters, Zigmond   +31 more
core   +1 more source