Results 91 to 100 of about 354 (204)

DAS-Based double-difference tomography of the NanAo offshore area: feasibility and initial result

Journal of Physics: Conference Series
Abstract The Shantou–Nan’ao offshore area in the northern South China Sea is characterized by frequent earthquakes related to the Littoral Fault Zone (LFZ), posing potential seismic risks to the coastal region. To characterize the crustal structure and fault geometry, this study uses distributed acoustic sensing (DAS) technology ...
Junda Wang, Qinnan Zhang, Jiaosheng Li, Shaoke Li, Muxi Wu, Chun Shan   +5 more
openaire   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Evaluation of safety of binary tamponade of vitreous cavity in surgical treatment of retinal detachment

Офтальмохирургия, 2013
Purpose. To assess the safety of retinal detachment surgery employing double endotamponade with PFCL and silicone oil for 30 days. Material and methods.
P.V. Lyskin, V.D. Zakharov, A.A. Shpak, E.G. Kazimirova, E.K. Pedanova, S.N. Ogorodnikova   +5 more
doaj  

Computed tomography-based radiostereometric analysis achieves sufficient precision for femoral implants in total knee arthroplasty: a randomized controlled trial

Journal of Orthopaedic Surgery and Research
Background Conventional radiostereometric analysis (RSA) has been used for several decades to assess implant migration in total knee arthroplasty (TKA).
Frank-David Øhrn, Lars H. W. Engseth, Are H. Pripp, Tommy Frøseth Aae, Anselm Schulz, Otto Schnell Husby, Stephan M. Röhrl   +6 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Double-difference traveltime tomography with edge-preserving regularization and a priori interfaces [PDF]

Geophysical Journal International, 2015
Youzuo Lin, Ellen M. Syracuse, Monica Maceira, Haijiang Zhang, Carene Larmat   +4 more
openaire   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

3-D variational inference-based double-difference seismic tomography method and application to the SAFOD site, California

Geophysical Journal International
SUMMARY Seismic tomography is used to image subsurface structures at various scales, accomplished by solving a nonlinear and non-unique inverse problem. It is therefore important to quantify velocity model uncertainties for accurate earthquake locations and geological interpretations.
Hao Yang, Xin Zhang, Haijiang Zhang
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source