Results 31 to 40 of about 307,789 (263)

The entry of unclosed autophagosomes into vacuoles and its physiological relevance.

open access: yesPLoS Genetics, 2022
It is widely stated in the literature that closed mature autophagosomes (APs) fuse with lysosomes/vacuoles during macroautophagy/autophagy. Previously, we showed that unclosed APs accumulated as clusters outside vacuoles in Vps21/Rab5 and ESCRT mutants ...
Zulin Wu   +17 more
doaj   +1 more source

The Effect of Reducing Vibration Of Lathe to Aisi 4340 Surface Roughness

open access: yesJurnal Teknik Mesin, 2023
One of the quality affected factors of machined products is surface roughness, which is affected by several factors, like force and vibration. Vibration is the derivation of deflection.
Gilang Awan Yudhistira   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

COMPARISON OF EFFECTIVENESS OF CLUSTER MAPPING, FLOW CHARTING, AND DOUBLE/ TRIPLE ENTRY ON TEACHING WRITING SKILL

open access: yesLitera, 2019
The study was aimed to examine the effectiveness of three writing techniques, namely Cluster Mapping, Flow Charting, and Double/ Triple Entry in improving the students’ writing skill.
Daniar Sofeny
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Digitalization of double entry bookkeeping and marketing of Wonogiri Cashew Farmers Group towards globalization

open access: yesAbdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang
This service focuses on digitizing bookkeeping and marketing in the cashew industry. Despite existing for over 20 years and has not developed. The team aims to address this issue by providing bookkeeping training for businesses, making their transactions
Heru Suwasono   +2 more
doaj   +1 more source

Ideal entry point and direction of retrograde intramedullary nailing of the tibia

open access: yesJournal of Orthopaedic Surgery and Research, 2023
Purpose To determine the ideal entry point and direction of retrograde intramedullary nailing of the tibia. Methods The imaging data of patients with distal tibial fractures from June 2020 to December 2021 in our hospital were collected, and computer ...
Min He   +4 more
doaj   +1 more source

Blockchains and Triple-Entry Accounting for B2B Business Models

open access: yesLedger, 2023
A blockchain is a distributed ledger (DL) that records and tracks of transactions on a P2P network. It was originally designed for cryptocurrencies, but it is now used in healthcare, supply chain management, finance, and many more fields due to its ...
Muhammad Imran Sarwar   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

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