eReply. Re: Morphological analysis and preoperative simulation of a double-chambered right ventricle using 3-dimensional printing technology [PDF]
, 2016 Takashi Shirakawa
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
La perplejidad del desdoblamiento
RecherchesOne of the most notable features of Jorge Luis Borges’ narrative is the peculiar use he makes of the theme of the double, specifically, in the plots and in the imaginary of his tales. Textual elements contribute to this, which are arranged and structured
Daniel Prasnicki Amaro
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Accessing the mitral valve: single-chamber or double-chamber technique? [PDF]
, 2022 Amer Harky +3 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Elliptic systems with bounded solutions and double phase functionals
Bruno Pini Mathematical Analysis SeminarWe study boundedness of weak solutions to elliptic systems of partial differential equations in divergence form, under the so-called p,q growth conditions. Examples are obtained by writing the Euler system of some double phase functionals.
Francesco Leonetti
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Search For Neutrinoless Double Beta Decay With Enriched 76Ge 1990-2003 -- HEIDELBERG-MOSCOW-Experiment [PDF]
, 2004 H. V. Klapdor‐Kleingrothaus +5 more
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Three-year duration of benefit from abciximab in patient receiving stents for acute myocardial infarction in the randomized double-blind ADMIRAL study [PDF]
, 2005 J. Dominguez
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source