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DNA double-strand break repair-pathway choice in somatic mammalian cells

open access: yesNature Reviews Molecular Cell Biology, 2019
The major pathways of DNA double-strand break (DSB) repair are crucial for maintaining genomic stability. However, if deployed in an inappropriate cellular context, these same repair functions can mediate chromosome rearrangements that underlie various ...
Rajula Elango   +2 more
exaly   +2 more sources
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Triplet of doubles: Double anterior chamber, double descemet membranes, and double rhexis

Medical Journal Armed Forces India, 2022
A 52-year-old women underwent penetrating keratoplasty for total corneal opacity after healed microbial keratitis with an uneventful postoperative period until six months when she developed gross diminution of vision. During examination, she was detected to have a membrane in the anterior chamber, creating a double anterior chamber with a total ...
Vijay K, Sharma   +3 more
openaire   +2 more sources

The Problem of Abortion and the Doctrine of the Double Effect

The Doctrine of Double Effect, 2020
One of the reasons why most of us feel puzzled about the problem of abortion is that we want, and do not want, to allow to the unborn child the rights that belong to adults and children.
P. Foot
semanticscholar   +1 more source

Double bubble, double trouble

Pediatric Surgery International, 2005
Duodenal atresia (DA) is not uncommon, either as an isolated anomaly or associated with trisomy 21, malrotation, or cardiac anomalies. It may be diagnosed on antenatal ultrasound by a "double-bubble" sign, which typically persists after birth on a plain abdominal radiograph.
H Okti, Poki, A J A, Holland, J, Pitkin
openaire   +2 more sources

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