Results 81 to 90 of about 8,606,277 (343)

Metacognitive ability is associated with reduced emotion suppression

open access: yesScientific Reports
Emotion regulation and metacognition are two key self-regulatory capacities that contribute significantly to psychological functioning. Emotion regulation involves the strategies individuals use to influence their emotional experiences, whereas ...
Kit S. Double
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Study on the influence of fracture geometric characteristics on the microscopic crack propagation and energy release mechanism in granite

open access: yesScientific Reports
Rockburst is a major safety risk in deep tunnel engineering, closely related to the propagation of fractures and energy release in rock masses. Therefore, a thorough understanding of the laws governing fracture propagation, energy release mechanisms, and
Tianzhuo Qin   +5 more
doaj   +1 more source

Genome-Wide Characterization of the Von Willebrand Factor a Gene Family in Wheat: Highlights Their Functional Roles in Growth and Biotic Stress Response

open access: yesPlants
Von Willebrand factor A (vWA) genes play important roles in regulating plant growth and development, as well as biotic stresses. However, limited data are available on the contributions of vWA genes to wheat (Triticum aestivum L.).
Luna Tao   +9 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Biomedical Ti–Nb–O alloy with high strength and ultra-low Young’s modulus

open access: yesMaterials Research Letters
In this study, a novel (α+β) dual-phase Ti–19Nb–0.6O was developed and processed via additive manufacturing, featuring ultra-low Young’s modulus of 42 GPa approximating that of human bone, coupled with high strength (919 MPa), and 15% elongation.
Yue Gao   +9 more
doaj   +1 more source

Bleeding Meckel′s diverticulum diagnosed and treated by double-balloon enteroscopy

open access: yesAvicenna Journal of Medicine, 2012
Meckel′s diverticulum (MD) is the most common congenital anomaly of the gastrointestinal (GI) tract. The diagnosis of symptomatic MD has been cumbersome.
Snorri Olafsson   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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