Results 141 to 150 of about 2,247,060 (230)
Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure
GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao +6 more
wiley +1 more source
A multifunctional 3D‐printed polymer–ZrO2 scaffold is developed to provide intrinsic radiopacity, photothermal responsiveness, and surface bioactivity. Reinforcement with ZrO2 enables real‐time x‐ray visibility and mechanical robustness, while a polydopamine coating facilitates near‐infrared‐triggered drug release and modulates cell migration, thereby ...
Sumin Kang +10 more
wiley +1 more source
Fetal MV/TV ratio offers a simple and reproducible marker of AAO in TGA with a cutoff of ≥ 1.0 accurately predicting the need for arch repair. This simple echocardiographic marker improves prenatal risk stratification and surgical planning, facilitating prenatal counseling. Abstract Introduction Transposition of great arteries (TGA) with coarctation of
Cosimo Marco Campanale +5 more
wiley +1 more source
Multiple cardiac malformations in a calf
This paper describes the morphopathological aspects of a case of multiple cardiac malformations in a calf. A two‐day‐old male calf of undefined breed was born with an ectopic heart, presenting with dyspnoea and in lateral recumbency. The owner had repositioned the exposed heart beneath the adjacent skin, which was suclosed, without additional incisions
LA Soares +7 more
wiley +1 more source
Genetics in Heterotaxy: A Case Series and Literature Review on DNAH9, PKD1L1, MMP21, and GDF1
Integrating trio‐based genomic sequencing with detailed clinical evaluation across seven French–Vietnamese heterotaxy cases alongside a review of 108 published patients reveals strong genotype–phenotype correlations. Variants in DNAH9, PKD1L1, MMP21, and GDF1 define a broad spectrum from isolated situs inversus to complex conotruncal heart defects and ...
Thi Bich Tuyen Ho +23 more
wiley +1 more source
Double Aortic Arch: An Uncommon Cause of Pediatric Airway Compression
Double aortic arch (DAA) is a rare congenital anomaly of the aortic arch that forms a complete vascular ring, causing compression of both the trachea and esophagus. The diagnosis is often made only after the child becomes symptomatic.
Avanish Kant Malhotra, Sambhunath Das
core +1 more source
ABSTRACT Background Postoperative delirium is a serious complication in intensive care units (ICUs), particularly following cardiac surgery. It is associated with circadian rhythm disruption, sleep disturbances and adverse outcomes. ICU environments often lack natural time cues, which may exacerbate circadian misalignment and increase delirium risk ...
Jolana Wagner‐Skacel +18 more
wiley +1 more source
Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study
Abstract Internal carotid artery (ICA) dissection is a rare and potentially devastating cause of cerebral ischaemia, initiated by an intimal tear or rupture of the vasa vasorum, that can lead to an intraluminal thrombus, vascular stenosis, occlusion, or dissecting aneurysm formation.
Damian M. Bailey +14 more
wiley +1 more source
Endothelial Matrin‐3 suppresses cellular senescence and protects against atherosclerosis. Matrin‐3 deficiency induces endothelial senescence, mitochondrial dysfunction, and activation of p53‐, cell cycle‐, and senescence‐related pathways. In atherosclerosis‐prone mice, endothelial Matrin‐3 deletion promotes atherosclerotic lesion formation and disrupts
Xiao Cheng +5 more
wiley +1 more source
Critical Tracheal Compression by a Double Aortic Arch in a Young Infant: A Case Report. [PDF]
Molatedi K +3 more
europepmc +1 more source

