Results 61 to 70 of about 49,151 (247)

Aortic Arch Phenotypes in Double Outlet Right Ventricle (DORV)—Implications for Surgery and Multi-Modal Imaging

Journal of Cardiovascular Development and Disease, 2022
Abnormal aortic arches (AAAs) cover a spectrum of malformations, including abnormal laterality, branching patterns, and flow-limiting narrowing, which themselves vary from tubular hypoplasia, through discrete coarctation, to complete interruption of the ...
Alessandro Gressani, Renata Aynetdinova, M. Kostolny, S. Schievano, Andrew C. Cook, Georgios Belitsis   +5 more
semanticscholar   +1 more source

Nanoparticle Drug Delivery Systems for Atherosclerosis: Precision Targeting, Inflammatory Modulation, and Plaque Stabilization

Advanced Science, EarlyView.
This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang, Feifei Li, Libo Liu, Ziyu An, Hanzhong Luo, Huan Zhang, Rui Ma, Ruoxi Zhang, Qiong Dai, Mingduo Zhang, Jinfan Tian, Chaoyong Liu, Xiantao Song, Yunfeng Lu   +13 more
wiley   +1 more source

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

Advanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez, Maria Virginia Giolito, Sultan Al‐Siyabi, Kristian Serafimov, Florine Laloux, Emeline Dierge, Léo Aubert, Céline Guilbaud, Selena Kaye, Paula Varon, Dorothée Marchand, Hanne Vlieghe, Emmanuel Hermans, Caroline Bouzin, Davide Brusa, Christiani Andrade Amorim, Barabara Pachikian, Yvan Larondelle, Cyril Corbet, Chantal Dessy, Olivier Feron   +20 more
wiley   +1 more source

Asymptomatic Balanced Double Aortic Arch Associated With Tetralogy of Fallot

World journal for pediatric & congenital heart surgery, 2020
Coexistence of asymptomatic balanced double aortic arch with tetralogy of Fallot (TOF) is extremely rare and represents a surgical dilemma in decision-making due to the lack of consensus on the management of this subset of patients.
M. Haranal, Haifa Abdul Latiff, Sivakumar Sivalingam   +2 more
semanticscholar   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source

Undiagnosed Double Aortic Arch in an Adult With Repaired Tetralogy of Fallot

JACC: Case Reports, 2019
Double aortic arch, the most common vascular ring, causes a complete ring surrounding the esophagus and trachea that leads to compressive symptoms. This report describes a young woman with a history of totally corrected tetralogy of Fallot who was a ...
Anita Sadeghpour, MD, Nakisa Khansari, MD, Marziyeh Pakbaz, MD, Kiara Rezaei Kalantari, MD, Hamidreza Pouraliakbar, MD, Maziar Gholampour Dehaki, MD   +5 more
doaj   +1 more source

Biodegradable Medical Implants: Reshaping Future Medical Practice

Advanced Science, EarlyView.
Biodegradable medical implants are transforming future healthcare by providing sustainable, biocompatible solutions that eliminate secondary removal procedures, enhancing patients’ physical and psychological comfort, and reducing economic burdens.
Bo Xia, Yan Liu, Yangkun Xing, Zhewei Shi, Xiaocheng Pan   +4 more
wiley   +1 more source

Evaluation of tracheal diameter and angles in fetuses with double aortic arch using prenatal ultrasound: implications for postnatal management

Frontiers in Medicine
ObjectiveThis study aims to analyze the value of prenatal ultrasound in the screening, diagnosis, and treatment of double aortic arch (DAA) malformations.MethodsA retrospective analysis was conducted on 31 fetal cases with double aortic arch anomalies ...
Caihong Jiang, Wen Ling, Longzhuang Peng, Shan Guo, Qiumei Wu, Chunxia Chen, Fa Chen, He Li, Zongjie Weng   +8 more
doaj   +1 more source

Successful Surgical Therapy of a Double Aortic Arch in a 10-Month-Old Mixed Breed Dog

Case Reports in Veterinary Medicine, 2019
A 10-month-old female spayed mixed breed dog with a suspected vascular ring anomaly was presented for exercise intolerance and wheezing. Computed tomography (CT) revealed a double aortic arch.
Christelle M. Follette, Alex Terreros, Sheldon L. Padgett   +2 more
doaj   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source