Results 211 to 220 of about 3,851,688 (392)

Long-lasting effect of penetrating acupuncture among responders: Double-blind RCT of acupuncture for vulvodynia. [PDF]

J Pain
Schlaeger JM, Steffen AD, Takakura N, Kobak WH, Takayama M, Yajima H, Suarez ML, Meinel M, Burke LA, Pauls HA, Yao Y, Sullivan KM, Glayzer JE, Foster DC, Kaptchuk TJ, Wilkie DJ.   +15 more
europepmc   +1 more source

Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial

The Lancet, 2014
M. Brose, C. Nutting, B. Jarzab, R. Elisei, S. Siena, L. Bastholt, C. Fouchardière, F. Pacini, R. Paschke, Y. Shong, S. Sherman, J. Smit, J. Chung, C. Kappeler, C. Peña, I. Molnár, M. Schlumberger   +16 more
semanticscholar   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source

Comments on: "Efficacy and Safety of Pregabalin for Restless Legs Syndrome in Korean Adults: A Randomized, Double-Blind, Placebo-Controlled Trial". [PDF]

J Clin Neurol
Kalam F, Kamal A, Anwer M.
europepmc   +1 more source

Prebiotics Affect the Fecal Microbiota and Gastrointestinal Health of Adults Participating in a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

, 2020
Annemarie Krug, Corinne N. Cannavale, Naiman A. Khan, Hannah D. Holscher   +3 more
openalex   +1 more source

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source

Adaptogenic Effects of Mushroom Blend Supplementation on Stress, Fatigue, and Sleep: A Randomised, Double-Blind, and Placebo-Controlled Trial. [PDF]

Brain Behav
Hisamuddin AS, Ramli F, Leo TK, Zain MSC, Wong MS, Suhaili MR, Lee LJ, Lee TY.   +7 more
europepmc   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

The Effectiveness of Bee Venom Acupuncture Therapy on the Treatment of Sprain of L-spine(A Randomized Controlled Trial; Double Blinding) [PDF]

, 2005
Kyung Tae Kim, Ho-Sueb Song
openalex  

A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression.

American Journal of Psychiatry, 2016
Jaskaran Singh, M. Fedgchin, E. Daly, P. de Boer, K. Cooper, P. Lim, C. Pinter, J. Murrough, G. Sanacora, R. Shelton, B. Kurian, A. Winokur, M. Fava, H. Manji, W. Drevets, L. van Nueten   +15 more
semanticscholar   +1 more source