Results 221 to 230 of about 2,907,437 (262)
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The Double-Blind Dilemma

JAMA: The Journal of the American Medical Association, 1973
To the Editor.— Double-blind studies have so often failed to add reliability to assays of therapeutic effectiveness that wits are now wont to say "it's the blind leading the blind." Though the procedure has merit in some situations, it will not prevent the poor observer from making false-positive or false-negative decisions. Rascals, on the other hand,
openaire   +3 more sources

Double-blind as a BHAT

JAMA: The Journal of the American Medical Association, 1985
To the Editor.— In assessing the "double-blindness" of the β-Blocker Heart Attack Trial, Byington and colleagues 1 have contributed an important set of observations. Their importance is magnified by the perceptive and well-written editorial of Dr Morgan.
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The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial.

New England Journal of Medicine, 1987
We conducted a double-blind, placebo-controlled trial of the efficacy of oral azidothymidine (AZT) in 282 patients with the acquired immunodeficiency syndrome (AIDS) manifested by Pneumocystis carinii pneumonia alone, or with advanced AIDS-related ...
M. Fischl   +12 more
semanticscholar   +1 more source

Directional DBS increases side‐effect thresholds—A prospective, double‐blind trial

Movement Disorders, 2017
The objective of this study was to investigate whether directional deep brain stimulation (DBS) of the subthalamic nucleus in Parkinson's disease (PD) offers increased therapeutic windows, side‐effect thresholds, and clinical benefit.
T. Dembek   +9 more
semanticscholar   +1 more source

Double-blind bind

Physics World, 2014
In reply to Penny Gowland's article "Turning a double-blind eye" (May p17) about the benefits of double- over single-blind peer review.
openaire   +3 more sources

Double-Blind Studies of Acupuncture

JAMA: The Journal of the American Medical Association, 1973
To the Editor.— Chein and Shapiro (224:1533, 1973) accept with reservations my objection (223:922, 1973) that double-blind studies of acupuncture are not feasible. (The reason is that correct placement of acupuncture needles requires cooperation of the patient in reporting paresthesias, a sensation of soreness, or mild discomfort, and, hence, renders ...
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Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double‐blind, randomized, controlled trial

Annals of Neurology, 2015
A 12‐month double‐blind sham‐surgery–controlled trial assessing adeno‐associated virus type 2 (AAV2)‐neurturin injected into the putamen bilaterally failed to meet its primary endpoint, but showed positive results for the primary endpoint in the subgroup
Warren Olanow   +23 more
semanticscholar   +1 more source

Physician Bias and the Double-Blind

Archives of General Psychiatry, 1969
IT IS A commonly accepted notion among some clinicians and most clinical investigators that the doctors' belief system, ie, his conviction as to the efficacy of his treatment and the treatability of his patient, can influence the outcome of treatment. 1-4 Despite some notes of reservation 5 the double-blind design has been considered an adequate means ...
Herbert M. Paley   +3 more
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The Difficulties of Double Blinding

Science, 2002
The recent publication of results from the Women's Health Initiative (WHI) study of hormone replacement therapy (HRT) suggests that the health risks of taking HRT may outweigh the benefits (“The vanishing promises of hormone replacement,” M. Enserink, News Focus, 19 July, p.
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