Results 81 to 90 of about 2,295 (232)

Exploring Calixarene‐Based Pseudorotaxane Architectures: Threading Ammonium Axles With an Exo‐Rim π‐Functionalized Calix[6]Arene Macrocycle

Chemistry – A European Journal, EarlyView.
This research presents a novel 1,4‐π‐functionalized calix[6]arene with enhanced interactions with dialkylammonium axles. We investigate threading behavior in CDCl3, highlighting how exo‐rim π‐functionalization affects binding affinity and stereoselectivity.
Veronica Iuliano, Paolo Della Sala, Placido Neri, Donato De Simone, Rocco Del Regno, Margherita De Rosa, Carmine Gaeta, Carmen Talotta   +7 more
wiley   +1 more source

Metal‐Ion Regulated Light‐Free Z→E Isomerization of Azobenzene Glycomacrocycle

Chemistry – A European Journal, EarlyView.
Metal ion‐catalyzed Z→E isomerization of photoswitchable azobenzene glycomacrocycle: A new azobenzene‐based glycomacrocycle is capable of forming a 1:1 complex with divalent metal ions in both E‐ and Z‐isomers. The complexes undergo light‐free Z→E isomerization in a timescale spanning from seconds to weeks.
Yang Zhou, Jinbiao Jiao, Mathieu Lordez, Jean‐Yves Salpin, Juan Xie   +4 more
wiley   +1 more source

Modulation of Epigenetic Control by Advanced Molecular Tweezers

Chemistry – A European Journal, EarlyView.
Tailored dimeric molecular tweezers recognize the DNA‐binding part of Histone H4 and interrupt the essential histone‐DNA interaction. ABSTRACT This work addresses the question if supramolecular systems can be tailored to interfere with posttranslational modifications (PTM) and epigenetics.
My‐Hue‐Le, Bianca Kamba, Anja Matena, Christine Beuck, Victoria Momand, Spiros Salvanos, Jessica Vossen, Mike Blueggel, Thomas Schrader, Peter Bayer   +9 more
wiley   +1 more source

Instability mechanism and failure characteristics of underground cavern in block system under the action of seismic waves

Deep Underground Science and Engineering, EarlyView.
Seismic waves with tensile stress, high amplitude, and low frequency are most likely to trigger block instability and sliding. Blocks with a single sliding surface are more prone to movement than those with multiple constraints, and roof‐positioned blocks are especially vulnerable to slide.
Xiao Wang, Jinxiao Liu, Gaoshuo Zhang, Wenxin Li, Changdi He   +4 more
wiley   +1 more source

Analytical stress solution framework for lined compressed air energy storage chambers and its application to safe burial depth determination and supporting effectiveness evaluation

Deep Underground Science and Engineering, EarlyView.
An analytical framework delivers a closed‐form stress solution for lined compressed air energy storage chambers, enabling the determination of the minimum safe burial depth. The solution quantitatively evaluates lining support effectiveness, offering a reliable tool for chamber design and optimization.
Zeyuan Sun, Cheng Zhao, Jinquan Xing, Qinyuan Luo   +3 more
wiley   +1 more source

Seismic analysis and design of tunnels within fault ground: A review

Deep Underground Science and Engineering, EarlyView.
The research methods of seismic response of tunnels within fault ground, including field investigations, analytical solutions, physical experiments, and numerical simulations, and seismic countermeasures are discussed. The present study examines the shortcomings and limitations of the current research and design, and puts forward proposals for future ...
Xingda Wang, Yujing Jiang, Xuepeng Zhang, Yuyong Jiao, Ningbo Li, Xiao Wang, Bo Li   +6 more
wiley   +1 more source

Investigation on tunnel stability considering pipe‐roof support with transparent soil technology

Deep Underground Science and Engineering, EarlyView.
This study integrates transparent soil technology, 3D reconstruction and numerical simulation to captures the full‐field deformation of shield tunnel instability. Results demonstrate that pipe‐roof support enhances stability via the “soil‐arching barrier effect,” effectively restraining failure wedge development by extending stress transfer paths ...
Zhi Jia, Yunpeng Ji, Zhao Lu, Honghua Zhao, Limin Zhang   +4 more
wiley   +1 more source

Tying a knot between crown ethers and porphyrins. [PDF]

Beilstein J Org Chem, 2023
Matviyishyn M, Szyszko B.
europepmc   +1 more source

Investigation on the mechanical behavior of the multiple‐layered lining structure of a water conveyance tunnel with high internal water pressure

Deep Underground Science and Engineering, EarlyView.
This study presents large‐scale similarity model testing (geometric ratio 3.6) of an innovative multiple‐layered lining system—comprising exterior precast segments, middle self‐compacting concrete, and an interior steel pipe—for high‐pressure (0.75 MPa) water conveyance tunnels.
Ramin Asadi, Shimin Wang, Chang Liu, Zhiyu Lin, Chuan He   +4 more
wiley   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source