Results 131 to 140 of about 4,903,274 (294)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Advances in Mechanical EngineeringThe theoretical prediction model for the dynamic performance of a double panel system that takes into account the effect of mechanical links is developed in this paper.
Yufei Zhang +3 more
doaj +1 more source
Chitosan-Raloxifene nanoparticle containing doxorubicin as a new double-effect targeting vehicle for breast cancer therapy. [PDF]
Daru, 2020 Mohammadi Z +3 more
europepmc +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Journal of Theoretical and Applied Electronic Commerce ResearchArtificial intelligence (AI) technologies are changing the ways of interaction between humans and machines, and smart interactions have become one of the hot topics of artificial intelligent in-home voice assistants (AVAs) by connecting humans, machines,
Jinyi He, Xinjian Liang, Jiaolong Xue
doaj +1 more source
Continuous deep sedation and the doctrine of double effect: Do physicians not intend to make the patient unconscious until death if they gradually increase the sedatives? [PDF]
Bioethics, 2020 Arima H.
europepmc +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Applied SciencesWhen an electric field is applied between two electrodes facing each other immersed in a liquid, the interfacial Pockels effect, a refractive index change proportional to the electric field, occurs in the electric double layer at the liquid–electrode ...
Kairi Morozumi +5 more
doaj +1 more source