Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Effects of Coenzyme Q10 Supplementation on Muscle Health and Physical Capacity in Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]
Liu X +6 more
europepmc +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
sox17 Mutagenesis Reveals Compounding Effects ofMaternal and Zygotic Contribution on Microglia Abundance. [PDF]
Spring CA +4 more
europepmc +1 more source
In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller +3 more
wiley +1 more source
Effects of acute or short-term oral sodium bicarbonate supplementation on high-intensity intermittent exercise performance and physiological responses in team-sport athletes: a systematic review and meta-analysis. [PDF]
Ge X, Sun H, Wu C, Liu S.
europepmc +1 more source
Effect of High-Intensity Laser Acupuncture on Muscle Performance, Pain, and Quality of Life in Patients with Chronic Nonspecific Low Back Pain: A Randomized Placebo-Controlled Trial [Letter]. [PDF]
Kumar R, Sharma S, Meel T.
europepmc +1 more source
Beyond Primum Non Nocere: Therapeutic Injury, Comparative Harm Management, and the Ethics of Modern Medicine. [PDF]
Nikolic B.
europepmc +1 more source

