Results 121 to 130 of about 16,005 (277)

HURDLE COUNT-DATA MODELS IN RECREATION DEMAND ANALYSIS

open access: yes
When a sample of recreators is drawn from the general population using a survey, many in the sample will not recreate at a recreation site of interest.
Shaw, W. Douglass   +1 more
core   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng   +14 more
wiley   +1 more source

Why don't households see the light? Explaining the diffusion of compact fluorescent lamps [PDF]

open access: yes
Many countries are currently considering bans on incandescent light bulbs and other policies to enhance the residential diffusion of energy-saving compact fluorescent lamps (CFLs).
Mills, Bradford F., Schleich, Joachim
core  

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

open access: yesAdvanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao   +10 more
wiley   +1 more source

SPANISH HOUSEHOLD DEMAND FOR SEAFOOD PRODUCTS

open access: yes
Consumption of seafood products in Spain has increased recently. Data from a nationally representative household budget survey are used. A double-hurdle model, applied to expenditures on fresh and processed seafood, shows the value of women's time ...
Manrique, Justo, Jensen, Helen H.
core   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng   +7 more
wiley   +1 more source

EATING OUT: AN IMPORTANT SOURCE OF FOOD FOR THE POOR AND THE FOOD INSECURE

open access: yes
Food consumption behaviors in food secure and food insecure households are compared. A two-stage budgeting and a double-hurdle model are used in the estimation. The results of the paper show that both food away from home and food at home are normal goods
Pan, Suwen, Jensen, Helen H.
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Tax-Deferred Retirement Savings of Farm Households: An Empirical Investigation

open access: yes
This study examines factors affecting tax-deferred retirement savings among farm households. A double-hurdle model is estimated using 2003 Agricultural Resource Management Survey (ARMS) farm-level national data. Results indicate that demographic factors,
Mishra, Ashok K., Chang, Hung-Hao
core   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

open access: yesAdvanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu   +9 more
wiley   +1 more source

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