Results 81 to 90 of about 1,476,773 (274)

Calculation of $P_ and $T_ odd effects in $"" sup 205_TIF including electron correlation

open access: yes, 2002
A method and codes for two-step correlation calculation of heavy-atom molecules have been developed, employing the generalized relativistic effective core potential and relativistic coupled cluster (RCC) methods at the first step, followed by ...
A. N. Petrov   +33 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Enhancing systematic literature review adapting ‘double diamond approach’

open access: yesHeliyon
Current literature review frameworks often lack quantification of literature volume, guidance on keyword inclusion, confidence in identifying knowledge gaps, and the formulation of research questions, which can lead to potential bias in research.
Hari Prasad Pandey   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Time-dependent Gutzwiller theory of magnetic excitations in the Hubbard model

open access: yes, 2003
We use a spin-rotational invariant Gutzwiller energy functional to compute random-phase-approximation-like (RPA) fluctuations on top of the Gutzwiller approximation (GA).
C. Attaccalite   +39 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

EVALUATION OF SAFETY OF DOUBLE TAMPONADE OF VITREOUS CAVITY IN SURGICAL TREATMENT OF RETINAL DETACHMENT

open access: yesОфтальмохирургия, 2015
Purpose. To assess the safety of retinal detachment surgery employing double endotamponade with PFCL and silicone oil for 30 days. Material and methods. Inclusion criteria: retinal detachment with retinal breaks located in both upper and lower retina and/
P. V. Lyskin   +5 more
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Evaluation of safety of binary tamponade of vitreous cavity in surgical treatment of retinal detachment

open access: yesОфтальмохирургия, 2013
Purpose. To assess the safety of retinal detachment surgery employing double endotamponade with PFCL and silicone oil for 30 days. Material and methods.
P.V. Lyskin   +5 more
doaj  

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