Results 71 to 80 of about 145,690 (265)

A double inverse problem for Fredholm integro-differential equation of elliptic type

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2014
In this paper the double inverse problem for partial differential equations is considered. The method of studying the one value solvability of the double inverse problem for a Fredholm integro-differential equation of elliptic type with degenerate kernel
Tursun K Yuldashev
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

A figuratrix for double integrals [PDF]

open access: yesTransactions of the American Mathematical Society, 1927
In a previous papert the writer has called attention to a number of the interesting properties of the figuratrix in the calculus of variations. It is the purpose of the present paper to define a figuratrix for double integrals and to develop some of its important characteristics. 1. A new form of the problem of double integrals.
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Double inequalities for quadrature formula of Gauss type with two nodes

open access: yesJournal of Numerical Analysis and Approximation Theory, 2008
In this paper upper and lower error bounds for Gauss's quadrature rule with two nodes are given.
Marius Heljiu
doaj   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Normalization of ZZ instanton amplitudes in type 0B minimal superstring theory

open access: yesJournal of High Energy Physics
We study ZZ instanton corrections in the (2, 4k) N $$ \mathcal{N} $$ = 1 minimal superstring theory with the type 0B GSO projection, which becomes the type 0B N $$ \mathcal{N} $$ = 1 super-JT gravity in the k → ∞ limit.
Vivek Chakrabhavi   +3 more
doaj   +1 more source

Some properties of a new general triple complex integral transform [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة
This paper investigates a novel triple complex integral transform, highlighting its properties and its applications to functional, integral, and partial differential equations.
Nada Mohammed   +2 more
doaj   +1 more source

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