Results 51 to 60 of about 3,153 (290)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

German Passives and English Benefactives

open access: yesNordlyd: Tromsø University Working Papers on Language & Linguistics, 2020
In both English benefactive constructions (John baked Mary a cake) and German kriegen/bekommen-passives (Er kriegte einen Stift geschenkt ‘He got a pen gifted’), the theme argument is accusative-marked but has no way of getting structural accusative case.
Vera Lee-Schoenfeld, Nicholas Twiner
doaj   +1 more source

Intercultural dialogues, hybridizations and identity building: a study of the CD Fogaréu by the goiano composer Bororó

open access: yesPer Musi, 2021
This article is linked to a research that had as object the double bass player and composer from Goiás Bororó, baptized as Dimerval Felipe da Silva. It was delimited as a universe of research the set of songs that integrate the CD Fogaréu, here perceived
Magda Miranda Clímaco   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The syntax of double object constructions in Cantonese [PDF]

open access: yes, 2007
This paper first demonstrates that Cantonese as a language does not have an exceptional order of non-subject arguments in double object constructions; rather, the verb bei2 'give' in this language, and this verb only, does.
Lam, OSC
core  

V-gei vs. double object construction

open access: yes, 2022
The present study investigates whether V-gei constructions [V-gei NP NP] have the same underlying syntactic structure as Double Object Constructions (DOC) [V NP NP], using a structural priming paradigm.
Liu, YH   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Double Object Constructions in Korean: Asymmetry between Theme and Goal [PDF]

open access: yes, 2004
Much of the generative studies on the double object constructions in English have shown that there exists an asymmetrical c-command relation between the Theme argument and the Goal argument: the Goal uniformly c-commands the Theme at D-structure.
Lee, Jung-Mo, Baek, Judy Yoo-Kyung
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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