The Dual Role of the Gut Microbiota in Cancer Chemoresistance
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi +3 more
wiley +1 more source
A Case of Refractory Peptic Ulcer with Choledochoduodenal Fistula Successfully Treated by Biliary Stent Placement Using an Ultrathin Endoscopic Rendezvous Technique: A Case Report. [PDF]
Miyashita Y +7 more
europepmc +1 more source
De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi +2 more
wiley +1 more source
Redefining the Treatment Landscape in Gastroparesis: A Clinical Review of Gastric Peroral Endoscopic Myotomy Outcomes and Therapeutic Integration. [PDF]
Essilfie-Quaye K +6 more
europepmc +1 more source
Role of ClpX and MsrA/B in the Oxidative and Cell Wall Stress Response in Bacillus anthracis Sterne
Methionine sulfoxide reductase (msrA/B) is an oxidative response enzyme that reduces oxidized methionine residues to maintain protein function. Surprisingly, loss of MsrA/B does not increase sensitivity to hydrogen peroxide or paraquat‐induced oxidative stress in Bacillus anthracis Sterne.
Aeron B. Pennington +5 more
wiley +1 more source
When Feeding Tubes Cause Biliary Disease: A Case of Acalculous Cholecystitis Due to Gastrostomy Tube Obstruction. [PDF]
Carrillo N +2 more
europepmc +1 more source
Macrophage: Biological Functions, Diseases, and Therapeutic Targets
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun +4 more
wiley +1 more source
Current Trends in Gastric Cancer Surgery and Postoperative Care. [PDF]
Park SH, Cho A, Kim DJ.
europepmc +1 more source
MYC in Oncogenesis and Therapeutic Implications
The MYC oncogene family (c‐MYC, N‐MYC, L‐MYC) functions as a central transcriptional hub orchestrating cancer progression through multiple interconnected pathways. This graphical abstract illustrates MYC's role as a multidimensional regulator positioned at the nexus of tumor microenvironment remodeling, metabolic reprogramming, and therapeutic ...
Na Zhang +5 more
wiley +1 more source
Assessment of Technical and Clinical Success of Percutaneous Transhepatic Biliary Drainage for Postoperative Bile Leaks: A Favorable Alternative to Early Surgical Revision? [PDF]
Misbahuddin-Leis M +6 more
europepmc +1 more source

