Results 51 to 60 of about 515 (214)

Complement Factor H‐Based Therapeutics: A Comprehensive Overview

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Complement factor H is a central regulator of the complement system and thus a target for therapeutic intervention. In this review, we provide an overview of past and current factor H‐based therapeutic concepts and modalities to treat complement‐mediated diseases.
Sebastiaan M. W. R. Hamers, Emmy J. Buter, Richard B. Pouw   +2 more
wiley   +1 more source

The Observational Signatures of Cosmic Strings [PDF]

, 2009
Cosmic strings were postulated by Kibble in 1976 and, from a theoretical point of view, their existence finds support in modern superstring theories, both in compactification models and in theories with extended additional dimensions.
Riccio, Giuseppe
core  

Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL‐23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease

Journal of Gastroenterology and Hepatology, Volume 41, Issue 7, Page 2006-2029, July 2026.
ABSTRACT Ulcerative colitis (UC) and Crohn's disease (CD) are increasingly prevalent in the Asia Pacific region, necessitating updated, region‐specific guidance on advanced therapies. Targeted small molecule agents, such as filgotinib, tofacitinib, upadacitinib, etrasimod, and ozanimod; and the IL‐23 p19 inhibitors (guselkumab, mirikizumab ...
Choon Jin Ooi, Khoon Lin Ling, Julajak Limsrivilai, Shu‐Chen Wei, Joyce Wing Yan Mak, Taku Kobayashi, Luan Minh Dang, Rupert W. Leong, Huiyu Lin, Meng‐Tzu Weng, Wan Chee Ong, Vineet Ahuja, Satimai Aniwan, Ryota Hokari, Wei Jie Jonathan Lee, Alex Hwong‐Ruey Leow, Wai‐Keung Leung, Wee‐Chian Lim, Govind Makharia, Katsuyoshi Matsuoka, Nazri Mustaffa, Siew‐Chien Ng, Mathew Philip, Pises Pisespongsa, Raja Affendi Raja Ali, Zhi Hua Ran, Marcellus Simadibrata, Jose Sollano, Malcolm Tan, Hang Dao Viet, Nik Razima Wan Ibrahim, Kai Chun Wu, Byong Duk Ye, Ida Hilmi, Asian Pacific Association of Gastroenterology (APAGE) Inflammatory Bowel Disease Committee and Asian Education Network in IBD (AEN‐IBD)   +34 more
wiley   +1 more source

350 μm dust emission from high-redshift quasars [PDF]

, 2006
We report detections of six high-redshift (1.8 ≤ z ≤ 6.4), optically luminous, radio-quiet quasars at 350 μm, using the SHARC II bolometer camera at the Caltech Submillimeter Observatory.
Dowell, C. Darren, Kovács, Attila, Frank Bertoldi, Beelen, Alexandre, Cox, Pierre, Carilli, Chris L., Alexandre Beelen, Attila Kovacs, Pierre Cox, Chris L. Carilli, Benford, Dominic J., Bertoldi, Frank, Alain Omont, C. Darren Dowell, Dominic J. Benford, Omont, Alain   +15 more
core   +1 more source

A Close Quasar Pair in a Massive Galaxy Merger at z = 5.7

The Astrophysical Journal Letters
Close quasar pairs are rare products of galaxy mergers in which both supermassive black holes (SMBHs) are actively accreting, offering strong constraints on merger-driven active galactic nuclei evolution.
Minghao Yue, Xiaohui Fan, Anna-Christina Eilers, Feige Wang, Jinyi Yang, Robert A. Simcoe   +5 more
doaj   +1 more source

Minimalist Footwear Acutely Alters Running Kinematics in Runners With Medial Tibial Stress Syndrome

Arthroscopy, Sports Medicine, and Rehabilitation, Volume 8, Issue 3, June 2026.
Purpose To assess immediate biomechanical changes in runners with medial tibial stress syndrome (MTSS) when transitioning from standard to minimalist running shoes. Methods Active runners diagnosed with MTSS ran on a treadmill at 10 km/h using standard and minimalist running shoes. Hip, knee, and ankle joint kinematics were captured using a 16‐infrared‐
Quyet Thang Nguyen, My T. Than, Minh Ho Ngoc, Ngoc‐Tram Nguyen, Nam Vu Tu, Tien Quang Tran, Dung Tran Trung   +6 more
wiley   +1 more source

HST Confirms Sub-5 kpc Dual Quasar Pairs at Cosmic Noon

The Astrophysical Journal
During cosmic noon ( z ∼ 1–3), when both star formation and black hole growth peaked, galaxy mergers are predicted to trigger dual active galactic nuclei that eventually coalesce as supermassive black hole (SMBH) binaries.
Qian Wang, Xuheng Ding, John Silverman, J. Xavier Prochaska, Tommaso Treu, Hassen M. Yesuf, Andrew D. Goulding, Masatoshi Imanishi, Nobunari Kashikawa, Issha Kayo, Kotaro Kohno, Kai Liao, Yoshiki Matsuoka, Michael A. Strauss, Shenli Tang   +14 more
doaj   +1 more source

Hidden No More: Spotlight on Tidal Disruption Events in Active Galactic Nuclei

Astronomische Nachrichten, Volume 347, Issue 5, June 2026.
ABSTRACT Tidal disruption events (TDEs) are typically discovered in previously quiescent galaxies. However, earlier studies have revealed a handful of TDEs occurring in pre‐existing active galactic nuclei (AGN). We discuss AT2019aalc, a promising TDE candidate in an AGN, and compare it to similar sources.
Patrik Milán Veres
wiley   +1 more source

Brain Health Deviation Index: A Comprehensive Brain Health Assessment Biomarker for Predicting Cognitive Decline and Polyvascular Stenosis

Brain Health, Volume 1, Issue 2, 24 June 2026.
ABSTRACT Assessing and quantifying brain health remains a pressing challenge, despite its importance for overall well‐being. Traditional methods that focus on isolated brain measures often fail to capture the multifaceted nature of brain health and may miss early signs of dysfunction.
Ziyang Liu, Shaodong Ding, Hao Liu, Jing Jing, Jian Cheng, Huaguang Zheng, Jiyang Jiang, Wei Wen, Zhe Zhang, Wanlin Zhu, Shiping Li, Yuesong Pan, Xueli Cai, Yijun Zhou, Chang Liu, Xia Meng, Yilong Wang, Hao Li, Yong Jiang, Haijun Niu, Nicole Kochan, Henry Brodaty, Tiemin Wei, Yubo Fan, Zixiao Li, Perminder S. Sachdev, Tao Liu, Yongjun Wang   +27 more
wiley   +1 more source

[O III] profile substructure in radio-quiet quasars [PDF]

, 2006
Interactions between the radio jet and the optical emission of the narrow-line region (NLR) are a well known phenomenon in Seyfert galaxies. Here, we present the study of possible jet-NLR interactions in five radio-quiet PG quasars with double or triple ...
Leipski, C., Bennert, N., C. Leipski, N. Bennert   +3 more
core   +2 more sources