Results 151 to 160 of about 2,272,539 (336)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Double lacunary sequence spaces of double sequence of interval numbers

, 2012
In this paper we introduce the concepts of double lacunary strongly convergence and double lacunary statistical convergence of double interval numbers. We prove some inclusion relations and study some of their properties.
openaire   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Some topological and algebraic properties of paranorm i-convergent double sequence spaces

Kuwait Journal of Science, 2013
In this article some new double sequence spaces  , ,   and   for  = (  a double sequence of positive real numbers have been introduced. Some algebraic and topological properties of these spaces have been studied.
BIPAN HAZARIKA
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Domain of difference matrix of order one in some spaces of double sequences [PDF]

, 2015
Serkan Demiriz, Osman Duyar
openalex   +1 more source

Magnetic Resonance Imaging (MRI) Double Inversion Recovery Sequence in Diagnosis of Multiple Sclerosis

, 2021
Ahmed Samir Ghonim, Rasha Lotfy Younes, Mohamed Amin Mohamed, Mohamed Fathy Dawoud   +3 more
openalex   +2 more sources

Two Algorithms for Deciding Coincidence In Double Temporal Recurrence of Eventuality Sequences [PDF]

, 2022
Babatunde Opeoluwa Akinkunmi, Adesoji A. Adegbola   +1 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Generalized Double Statistical Convergence Sequences on Ideals in Neutrosophic Normed Spaces

, 2023
M. Jeyaraman, S. Iswariya., R. Pandiselvi   +2 more
openalex   +2 more sources