Results 201 to 210 of about 929,781 (297)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Effect of TAR hairpin stabilization on HIV-1 reverse transcription. [PDF]

J Virol
Da Silva Amaral S, Richetta C, Oualid L, Tu NQ, René B, Mauffret O, Delelis O, Fossé P.   +7 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Sequence Specific Recognition of Double Helical DNA

CHIMIA, 1993
Peter B. Dervan
doaj   +2 more sources

How mutagenesis and laboratory conditions affect the genome of the metal-resistant bacterium <i>Cupriavidus metallidurans</i> strain CH34. [PDF]

J Bacteriol
Große C, Dreyer V, Schulz V, Schleuder G, Kohl TA, Herzberg M, Dobritzsch D, Fuszard M, Niemann S, Nies DH.   +9 more
europepmc   +1 more source

Double stranded DNA sequencing as a choice for DNA sequencing

Nucleic Acids Research, 1988
H, Zhang, R, Scholl, J, Browse, C, Somerville   +3 more
openaire   +3 more sources

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Origins and breadth of pairwise epistasis in an α-helix of β-lactamase TEM-1. [PDF]

Nat Commun
Birgy A, Roussel C, Kemble H, Mullaert J, Panigoni K, Chapron A, Magnan M, Jacquier H, Cocco S, Monasson R, Tenaillon O.   +10 more
europepmc   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Champuru 2: Improved Scoring of Alignments and a User-Friendly Graphical Interface. [PDF]

Mol Ecol Resour
Spöri Y, Flot JF.
europepmc   +1 more source