Results 181 to 190 of about 3,006,358 (252)

Impact of Cistron Topology and Bicistronic Vector Design in the piggyBac Transposon System for Improved Antibody Expression. [PDF]

Biotechnol J
Vitko J, King T, Aral E, McLellan S, Divello H, Maimouni S, McLamarrah T, Tedstone J, Cairns V, DeMaria C, Scarcelli JJ.   +10 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

On Statistical Convergence of Double Sequences of Closed Sets

In this paper, we introduce the concepts of statistical inner and statistical outer limits for double sequences of closed sets and give some formulas for finding these limits.
Sever, Y, Talo, Ö
core  

Enhancing prediction accuracy for enzyme activity engineering through sequence co-evolution and epistatic relationship modeling. [PDF]

Nucleic Acids Res
Kim DN, Kim H, Kim D, Jung GY, Kim S, Noh MH.   +5 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

In Vitro Chromosome Translocations: Modeling Critical Drivers of Human Neoplasms. [PDF]

Curr Issues Mol Biol
Tynyshtykbayeva N, Varga K, Lukacsi S, Fabian Z.   +3 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Double dominating sequences in bipartite and co-bipartite graphs

Discussiones Mathematicae Graph Theory
Gopika Sharma, Arti Pandey
doaj   +1 more source

Impaired Motor Function in a Zebrafish Stathmin-2 Knockout Model. [PDF]

Dev Neurobiol
Gurberg TJN, Harji ZA, Rampal CJ, Sacy-Richer J, Wang A, Rodríguez EC, Armstrong GAB.   +6 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source