Results 171 to 180 of about 75,052 (236)

Temporal lobe epilepsy is associated with neuroinflammation, extracellular matrix remodeling, and synaptic protein alterations. [PDF]

Front Mol Neurosci
Auer S, Hoffmann L, Schicht M, Blümcke I, Paulsen F.   +4 more
europepmc   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet, Anna Largajolli, Petra M. Jauslin, Emilie Schindler, Mourad Hamimed, Wannee Kantasiripitak, Antonio Gonçalves, Eline Van Maanen, Khaled Benkali, Tomohisa Saito, Jonathan I. Silverberg, Andreas Wollenberg, Michael Graeber, Liliana Ulianov, Christophe Piketty, Luca Loprete, Vincent Duval, Nathalie Wagner   +17 more
wiley   +1 more source

Cruciform-forming AT/TA repeats are acted upon by structure-selective endonucleases and Rad51 prior to repositioning to the nuclear periphery for repair. [PDF]

Nucleic Acids Res
Boer JL, Crippen SM, Kim AJ, Kramer DN, Theulot B, Dovrat D, Aharoni A, Smith DJ, Freudenreich CH.   +8 more
europepmc   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Happier individuals generate more spontaneous thoughts about friends and value relationships over money. [PDF]

Commun Psychol
Shin WG, Ahn J, Choe KW, Lee H, Han J, Lee E, Lux BK, Woo CW, Choi I, Sul S.   +9 more
europepmc   +1 more source

The Role of Sustainable Social Media Marketing Activities in Raising Bottom‐of‐the‐Pyramid Customers' Engagement, Satisfaction, and Subjective Well‐Being

Business Strategy and the Environment, EarlyView.
ABSTRACT Though prior studies have explored the effects of firms' social media marketing activities on customer engagement, the dynamics characterizing this association in bottom‐of‐the‐pyramid (BoP) markets remain tenuous, exposing a critical gap. Addressing this gap, we develop and test a model assessing (a) the effects of firms' sustainable social ...
Md. Al Amin, Md Masudur Rahman, Linda D. Hollebeek, Jamid Ul Islam, Moira K. Clark   +4 more
wiley   +1 more source

Estimating the minimal important change of single-item measures using the adjusted predictive modeling method or the longitudinal confirmatory factor analysis method. [PDF]

Qual Life Res
Terluin B, Pua YH, Fromy P, Trigg A, van der Zwaard B, Bjorner JB.   +5 more
europepmc   +1 more source

Merging Psychological, Social, and Rational Perspectives: A Study of the Determinants of Consumer Choices for Sustainable Furniture

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines consumer purchase intentions for a sofa produced through industrial symbiosis (IS), utilizing recycled textiles and fibers. As a high‐investment product, the IS sofa requires a significant financial commitment and involves complex decision‐making, an area less studied compared with other sustainable goods categories.
Rosa Maria Dangelico, Luca Fraccascia, Valerio Schiaroli   +2 more
wiley   +1 more source

Integrative human intervention study for mycotoxin biomarker discovery and toxicokinetic characterization. [PDF]

Sci Rep
Visintin L, Alladio E, Nicolás MG, De Saeger S, Lu EH, Chiu WA, Goessens T, De Boevre M.   +7 more
europepmc   +1 more source