Results 71 to 80 of about 3,201 (168)
The Doublesex Homolog Dmrt5 is Required for the Development of the Caudomedial Cerebral Cortex in Mammals [PDF]
Cerebral Cortex, 2012 Regional patterning of the cerebral cortex is initiated by morphogens secreted by patterning centers that establish graded expression of transcription factors within cortical progenitors. Here, we show that Dmrt5 is expressed in cortical progenitors in a high-caudomedial to low-rostrolateral gradient.
Saulnier A +18 more
openaire +3 more sources
Phylogenetic analysis and embryonic expression of panarthropod Dmrt genes
Frontiers in Zoology, 2019 Background One set of the developmentally important Doublesex and Male-abnormal-3 Related Transcription factors (Dmrt) is subject of intense research, because of their role in sex-determination and sexual differentiation.
Virginia Panara +2 more
doaj +1 more source
Molecular Reproduction and Development, Volume 93, Issue 4, April 2026.Post‐metamorphic gonadal development in Xenopus tropicalis was analyzed through integrated morphometric, histological, and transcriptional approaches. Males showed upregulation of cyp17, amh, and amhr2, whereas females exhibited an increased aldh1a2 and ddx4.
Daniele Marini +3 more
wiley +1 more source
PLoS Genetics, 2012 The formation or suppression of particular structures is a major change occurring in development and evolution. One example of such change is the absence of the seventh abdominal segment (A7) in Drosophila males.
David Foronda +2 more
doaj +1 more source
Molecular evolution of Drosophila Sex-lethal and related sex determining genes
BMC Evolutionary Biology, 2012 Background Sex determining mechanisms are evolutionarily labile and related species often use different primary signals and gene regulatory networks. This is well illustrated by the sex determining cascade of Drosophila fruitflies, which have recruited ...
Mullon Charles +2 more
doaj +1 more source
The transformer gene controls sexual development in Drosophila suzukii
Insect Science, Volume 33, Issue 2, Page 547-565, April 2026.The transformer gene plays a key role in the genetic pathway for sexual development in Drosophila suzukii Abstract The genetic network of sex determination in the model organism Drosophila melanogaster was investigated in great detail. Such knowledge not only advances our understanding of the evolution and regulation of sexual dimorphism in insects ...
Ying Yan +8 more
wiley +1 more source
Frontiers in Physiology, 2020 The intersex (ix) gene acts in concert with doublesex (dsx) at the end of the sex determination hierarchy to control somatic sexual differentiation in Drosophila melanogaster.
Yating Liu +7 more
doaj +1 more source
Genetic engineering for SIT application: a fruit fly‐focused review
Insect Science, Volume 33, Issue 2, Page 703-723, April 2026.Abstract Sterile insect technique (SIT) has become a key component of efficient pest control. Fruit fly pests from the Drosophilidae and Tephritidae families pose a substantial and overwhelmingly increasing threat to the agricultural industry, aggravated by climate change and globalization among other contributors.
Serafima Davydova +2 more
wiley +1 more source
Runaway evolution of the male-specific exon of the doublesex gene in Diptera [PDF]
Gene, 2011 In Diptera (Insecta), alternatively spliced male-specific and female-specific products of the doublesex (dsx) gene play a key role in regulating development of the adult genital structures from the genital disc. Analysis of the pattern of nucleotide substitution of different domains of the dsx gene in 29 dipteran species showed that, over short ...
openaire +2 more sources