Results 61 to 70 of about 5,765 (162)
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
British Journal of Pharmacology, EarlyView.Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Trivial doubly warped products
FilomatThe aim of the paper is to provide new obstructions to the existence of doubly warped products. We prove that, if the factor manifolds of a doubly warped product are connected and locally product Riemannian manifolds, then, the almost product structure naturally induced on the doubly warped product is parallel if and only if the manifold is
openaire +1 more source
Fused Collapsing for Wide BVH Construction
Computer Graphics Forum, EarlyView.Abstract We propose a novel approach for constructing wide bounding volume hierarchies on the GPU by integrating a simple bottom‐up collapsing procedure within an existing binary bottom‐up BVH builder. Our approach directly constructs a wide BVH without traversing a temporary binary BVH as done by previous approaches and achieves 1.4 – 1.6 × lower ...
Wilhem Barbier, Mathias Paulin
wiley +1 more source
Style Brush: Guided Style Transfer for 3D Objects
Computer Graphics Forum, EarlyView.We introduce Style Brush, a guided 3D style‐transfer method for textured meshes that provides precise creative control. It supports the use of multiple style images, smooth transitions and intuitive guidance, producing visually appealing textures that follow user intent as we demonstrate in our user study and results. Abstract We introduce Style Brush,
Áron Samuel Kovács +2 more
wiley +1 more source
Variable‐Rate Texture Compression: Real‐Time Rendering with JPEG
Computer Graphics Forum, EarlyView.Abstract Although variable‐rate compressed image formats such as JPEG are widely used to efficiently encode images, they have not found their way into real‐time rendering due to special requirements such as random access to individual texels. In this paper, we investigate the feasibility of variable‐rate texture compression on modern GPUs using the ...
Elias Kristmann +2 more
wiley +1 more source
Terrain Synthesis and Authoring based on Iso‐Contours
Computer Graphics Forum, EarlyView.Abstract Digital terrains are central to realistic landscape depiction, yet authoring tools must balance perceptual realism with intuitive artistic control. We propose a compact vector‐based representation that models terrain as nested iso‐contours, inspired by geomorphology and cartography.
B. Huftier +5 more
wiley +1 more source
Non‐Rigid 3D Shape Correspondences: From Foundations to Open Challenges and Opportunities
Computer Graphics Forum, EarlyView.Abstract Estimating correspondences between deformed shape instances is a long‐standing problem in computer graphics; numerous applications, from texture transfer to statistical modelling, rely on recovering an accurate correspondence map. Many methods have thus been proposed to tackle this challenging problem from varying perspectives, depending on ...
A. Zhuravlev +14 more
wiley +1 more source
On compact Einstein doubly warped product manifolds
Tamkang Journal of Mathematics, 2018 In this paper, the non-existence of connected, compact Einstein doubly warped product semi-Riemannian manifold with non-positive scalar curvature is proved. It is also shown that there does not exist non-trivial connected Einstein doubly warped product semi-Riemannian manifold with compact base $B$ or fibre $F$.
openaire +2 more sources
NAADF: Globally Illuminated Voxel Worlds Accelerated with Nested Axis‐Aligned Distance Fields
Computer Graphics Forum, EarlyView.Abstract Achieving realistic rendering of 3D scenes in real time using path tracing is challenging due to the high sample count required, with ray tracing as the bottleneck. Focusing on voxels as a geometry representation offers significant opportunities for optimizations, especially for tracing the rays, but also for computing the samples.
A. Ulschmid +4 more
wiley +1 more source
Ricci solitons on singly warped product manifolds and applications
, 2019 TThe purpose of this article is to study the inheritance properties of Ricci soliton warped product manifolds by their factor manifolds. First, it is proved that being a Ricci soliton is an inheritance property.
Shenawy, Sameh
core