Results 21 to 30 of about 1,257,306 (334)

Forest stand productivity derived from site conditions: an assessment of old Douglas-fir stands (Pseudotsuga menziesii (Mirb.) Franco var. menziesii) in Central Europe

Annals of Forest Science, 2019
Douglas-fir growth correlates with the climate, the soil moisture regime, and the soil nutrient status, reflecting a broad physiological amplitude.
Tamara Eckhart, E. Pötzelsberger, R. Koeck, Dominik Thom, G. Lair, Marcela van Loo, H. Hasenauer   +6 more
semanticscholar   +1 more source

Disruption of the grid cell network in a mouse model of early Alzheimer’s disease

Nature Communications, 2022
It remains poorly understood how the onset of Alzheimer’s disease affects spatial cognition. Here, the authors report that spatial coding in grid cells deteriorates over time in a mouse model of Alzheimer’s disease during the early stages of pathology ...
Johnson Ying, Alexandra T. Keinath, Raphael Lavoie, Erika Vigneault, Salah El Mestikawy, Mark P. Brandon   +5 more
doaj   +1 more source

The Douglas-Fir Genome Sequence Reveals Specialization of the Photosynthetic Apparatus in Pinaceae

G3: Genes, Genomes, Genetics, 2017
A reference genome sequence for Pseudotsuga menziesii var. menziesii (Mirb.) Franco (Coastal Douglas-fir) is reported, thus providing a reference sequence for a third genus of the family Pinaceae.
D. Neale, P. McGuire, N. Wheeler, Kristian Stevens, M. Crepeau, Charis M. Cardeño, A. Zimin, A. Zimin, D. Puiu, G. Pertea, U. Sezen, C. Casola, Tomasz E. Koralewski, Robin Paul, D. Gonzalez-Ibeas, S. Zaman, R. Cronn, M. Yandell, C. Holt, C. Langley, J. Yorke, S. Salzberg, J. Wegrzyn   +22 more
semanticscholar   +1 more source

Does level of motivation for change impact post-treatment outcomes in the eating disorders? Protocol for a systematic review with quantitative analysis

Journal of Eating Disorders, 2017
Background Eating Disorders are highly prevalent and widespread mental health problems, with marked risk of chronicity and refractoriness to treatment.
Jeanne Sansfaçon, Howard Steiger, Lise Gauvin, Émilie Fletcher, Mimi Israël   +4 more
doaj   +1 more source

Optogenetic gamma stimulation rescues memory impairments in an Alzheimer’s disease mouse model

Nature Communications, 2019
Slow gamma oscillations are associated with memory and have been reported to be disrupted in patients with Alzheimer’s disease. Here the authors show that optogenetic stimulation of medial septum parvalbumin neurons at 40 Hz rescues memory retrieval in ...
Guillaume Etter, Suzanne van der Veldt, Frédéric Manseau, Iman Zarrinkoub, Emilie Trillaud-Doppia, Sylvain Williams   +5 more
doaj   +1 more source

Cellular and molecular inflammatory profile of the choroid plexus in depression and suicide

Frontiers in Psychiatry, 2015
The inflammatory hypothesis of depression is one of the main theories that endeavors to explain and describe the underlying biological mechanisms of depression and suicide.
Julia eDevorak, Julia eDevorak, Susana Gabriela eTorres-Platas, Susana Gabriela eTorres-Platas, Maria Antonietta eDavoli, Josée ePrud'homme, Gustavo eTurecki, Gustavo eTurecki, Gustavo eTurecki, Naguib eMechawar, Naguib eMechawar, Naguib eMechawar   +11 more
doaj   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Loss of dysbindin-1 in excitatory neurons in mice impacts NMDAR-dependent behaviors, neuronal morphology and synaptic transmission in the ventral hippocampus

Scientific Reports
Dysbindin-1, a protein encoded by the schizophrenia susceptibility gene DTNBP1, is reduced in the hippocampus of schizophrenia patients. It is expressed in various cellular populations of the brain and implicated in dopaminergic and glutamatergic ...
Sanjeev K. Bhardwaj, Moushumi Nath, Tak Pan Wong, Lalit K. Srivastava   +3 more
doaj   +1 more source

Semantic elaboration in auditory and visual spatial memory

Frontiers in Psychology, 2010
The aim of this study was to investigate the hypothesis that semantic information facilitates auditory and visual spatial learning and memory. An auditory spatial task was administered, whereby healthy participants were placed in the center of a semi ...
Meghan eTaevs, Louisa eDahmani, Robert J Zatorre, Veronique D Bohbot   +3 more
doaj   +1 more source