Results 41 to 50 of about 1,148,530 (239)

Memory and Plasma pTau217 Refine Prognosis in Down Syndrome

Annals of Neurology, EarlyView.
Individuals with Down syndrome (DS) are at high risk for Alzheimer's disease (AD), yet accessible tools for routine clinical screening of AD in individuals with DS remain limited. Using data from the Alzheimer Biomarker Consortium‐Down Syndrome (ABC‐DS), we show that integrating plasma pTau217 with performance on the modified cued recall task ...
Casey R. Vanderlip, Sigan L. Hartley, Sharon Krinsky‐McHale, Christy Hom, Adam M. Brickman, Melissa E. Petersen, Elizabeth Head, Craig E.L. Stark, for the Alzheimer's Biomarker Consortium—Down Syndrome (ABC‐DS) Study Team, Beau M. Ances, Howard F. Andrews, Karen Bell, Rasmus M. Birn, Adam M. Brickman, Peter Bulova, Jeff Burns, Amrita Cheema, Kewei Chen, Bradley T. Christian, Isabel Clare, Ann D. Cohen, Eric W. Doran, Tatiana M. Foroud, Benjamin L. Handen, Jordan Harp, Sigan L. Hartley, Elizabeth Head, Denise Head, Christy Hom, Lawrence Honig, Milos D. Ikonomovic, Sterling C Johnson, M. Ilyas Kamboh, David Keator, Julia K. Kofler, William Charles Kreisl, Sharon J. Krinsky‐McHale, Florence Lai, Patrick Lao, Charles Laymon, Joseph Hyungwoo Lee, Ira T. Lott, Victoria Lupson, Mark Mapstone, Davneet Singh Minhas, Neelesh Nadkarni, Sid O'Bryant, Deborah Pang, Melissa Petersen, Julie C. Price, Lauren Ptomey, Margaret Pulsifer, Michael S. Rafii, Herminia Diana Rosas, Frederick Schmitt, Nicole Schupf, Wayne P. Silverman, Dana L. Tudorascu, Rameshwari Tumuluru, Badri Varadarajan, Michael A. Yassa, Shahid Zaman, Fan Zhang   +62 more
wiley   +1 more source

Detecção de Candida albicans fosfolipidolíticas isoladas da saliva de crianças com síndrome de Down.

Acta Médica Portuguesa, 2002
The childhood is one of the most propitious period of the life to the occurrence of infection by yeasts of the genus Candida. In children with Down's syndrome, besides the predispose factors to bucal candidiasis; macroglossia, bucal muscular incompetence,
Evandro L Ribeiro, C De Castro Campos, A M Costa Crespo, Jovirês S Castro, Frederico P Rocha, Marcella Alves, Mariella S Goulart, Cléver Cardoso, Wesley Ferreira, Plínio Lázaro Naves, A José Soares, Simone R Miranda, Fabiana C Pimenta   +12 more
doaj   +1 more source

A cytogenetic Study of Down’s Syndrome in Iraqi Population

, 2023
Down’s syndrome is the most common type of chromosomal abnormality found in neonates. It is associated with characteristic abnormal facial features and mental retardation. However, clinical diagnosis is not sufficient to confirm the disease.
Saad Abdulbaqi Alomar
core  

Autism Screening in the First Year and Beyond: Comparison of Multiple Measures

Autism Research, EarlyView.
ABSTRACT Autism screening aids in early detection and diagnosis. Several screeners are available for toddlers 16 months and older, but there is little data on the accuracy of screening measures used in the first year of life. A community sample (N = 1641) completed three screeners—M‐CHAT‐R, ITC, VIRSA—online at 6, 9, 12, 18, and 24 months of age ...
Devon N. Gangi, Chandni Parikh, Monique Moore Hill, Shyeena Maqbool, Rachel Ni, Simon Dvorak, Gregory S. Young, Sally Ozonoff   +7 more
wiley   +1 more source

Characterization of Anticholinergic Medication Use and Its Associations With Everyday Memory Problems and Cognitive Decline in Autistic Adults With Higher Support Needs

Autism Research, EarlyView.
ABSTRACT Among older adults in the general population, medications with anticholinergic (AC) effects are associated with declines in cognitive functioning and with dementia and Alzheimer's disease. Autistic people have high rates of co‐occurring medical conditions and polypharmacy across the lifespan; thus, they may be at particularly high risk of ...
Goldie A. McQuaid, Nancy Raitano Lee, Gregory L. Wallace   +2 more
wiley   +1 more source

Tongue carcinoma in an adult Down's syndrome patient: a case report

World Journal of Surgical Oncology, 2009
Background Cancer of the oral cavity is rare and unusual in Down's syndrome patient. The over all risk is similar to that in adult population. Case presentation This case report describes a 27 years old male with Down's syndrome, non-smoker, who ...
Serhal Jamal, Natout Mohamed, Geara Fady, Farhat Fadi S, Daya Walid   +4 more
doaj   +1 more source

Hippocampal Changes in Down’s Syndrome

, 1995
Semiquantitative scales and quantitative computerized image analyses were used to determine the neurofibrillary tangle formation and AB amyloid deposition in the hippocampal formation and inferior temporal gyrus in 36 Down’s syndrome cases, aged 4 to 73 ...
J Gordon Millichap
core   +1 more source

Quality of Life in Autism: A Systematic Review and Meta‐Analysis of Patients and Caregivers

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition associated with significant challenges in daily functioning and well‐being. Caregivers often experience substantial psychological and physical burden. However, comprehensive synthesis of quality of life (QoL) outcomes for both individuals with ASD and their caregivers ...
Kamila Castro, Camila Kümmel Duarte, Eduarda Silva, Laura Hoffmann, Jenifer Lopes Borchardt, Laura Pohl, Josiane Luçardo, Myrella Lapschies, Andreia Morales Cascaes, Ana Amélia Freitas‐Vilela, Adriane Cenci, Juliana S. Vaz   +11 more
wiley   +1 more source

Assessment of the relationship between joint laxity and migration of the hip in children with down syndrome

Journal of Children's Orthopaedics, 2012
Purpose The aim of this cross-sectional cohort study is to describe the incidence of joint laxity and the correlation between joint laxity and radiological migration of the hip in children with Down syndrome. Methods Sixty-five children (2–19 years) with
R. Eshuis, M. Boonzaaijer, H. van Wieringen, J. E. H. Pruijs, R. J. B. Sakkers   +4 more
doaj   +1 more source

Listening to young children with disabilities: Experiences of quality in mainstream primary education

British Educational Research Journal, EarlyView.
Abstract All children should have access to quality education through a child‐centred pedagogy. An inclusive, child‐centred pedagogy uses a strength‐based view of children that recognises each child as unique and competent, providing children with multiple opportunities to explore and learn at their own pace.
Katherine Gulliver
wiley   +1 more source