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open access: yesCoSMO, 2023
Andrea Brondino, John Greaney
doaj   +1 more source

ggalign: Bridging the Grammar of Graphics and Biological Multilayered Complexity

open access: yesAdvanced Science, EarlyView.
The ggalign package provides a comprehensive framework for composable visualization built on top of ggplot2. Its primary purpose is to enable the construction of complex multi‐plot layouts with consistent observation alignment across plots, particularly for high‐dimensional data contexts such as genomics, transcriptomics, and microbiome studies ...
Yun Peng   +9 more
wiley   +1 more source

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

open access: yesAdvanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang   +14 more
wiley   +1 more source

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open access: yesCoSMO, 2023
Andrea Brondino, John Greaney
doaj   +1 more source

SemiLT: A Multianchor Transfer Learning Method for Cross‐Modality Cell Label Annotation from scRNA‐seq to scATAC‐seq

open access: yesAdvanced Science, EarlyView.
A multianchor transfer learning method, SemiLT, enables accurate cell label annotation in sparse scATAC‐seq data by leveraging well‐annotated scRNA‐seq references. By addressing temporal discrepancies between modalities, SemiLT improves rare cell type identification and batch correction.
Zhitong Chen   +3 more
wiley   +1 more source

Dyslexia Data Consortium: A Comprehensive Platform for Neuroimaging Data Sharing, Analysis, and Advanced Research in Dyslexia. [PDF]

open access: yesNeuroinformatics
Phatangare RV   +5 more
europepmc   +1 more source

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