Results 121 to 130 of about 10,165,257 (315)
Advanced Science, EarlyView.LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li +8 more
wiley +1 more source
Advanced Science, EarlyView.STMIGCL is an implicit contrastive learning‐based multi‐view graph convolutional network framework designed for downstream tasks such as spatial domain recognition, trajectory inference, and spatially variable gene identification. By combining multi‐view learning with contrastive learning and employing contrastive learning methods that enhance contrast
Sheng Ren +5 more
wiley +1 more source
A Scheme for Return Channel Utilization for Efficient Download of Data Broadcasting Applications [PDF]
, 2005 Seung-Mi Kang +2 more
openalex +1 more source
Advanced Science, EarlyView.Box C/D snoRNP complex regulates protein translation. This study identifies ZNHIT3 as a key component of the complex and ensures normal protein expression, including transcription factors orchestrating cell fate commitment, during early mouse embryogenesis.
Guanghui Yang, Qiliang Xin, Jurrien Dean
wiley +1 more source
Advanced Science, EarlyView.The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou +11 more
wiley +1 more source
Waiting for the Download: A New Metaphor to Describe Education [PDF]
, 2006 John W. Murphy, Jung Min Choi
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MRAS: Master Regulator Analysis of Alternative Splicing
Advanced Science, EarlyView.This study developed a computational approach called MRAS, designed to identify master regulators of splicing differences across various biological contexts. In this framework, altered RBP expression, rather than spliceosomal mutations or other modifications, plays a central role in driving these splicing differences.
Lei Zhou +9 more
wiley +1 more source
Advanced Science, EarlyView.In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han +10 more
wiley +1 more source