Results 271 to 280 of about 11,015,246 (337)

Fusidic Acid Reverses Chemoresistance in Breast Cancer via Targeting DDX6 to Downregulate GSK‐3β/β‐Catenin Signaling

Advanced Science, EarlyView.
FA directly binds to residue H378 of DDX6 and promotes its interaction with HSC70, leading to CMA degradation of DDX6, thereby impairing GSK‐3β/β‐catenin signaling, inhibiting ABC transporter proteins, and enhancing chemosensitivity. Abstract ABC transporter protein‐mediated drug efflux is a significant contributor to induced resistance in breast ...
Xiaxia Fan, Dan Guo, Songtao Li, Jinmiao Tian, Chaotong Zhang, Zhuoyu Li   +5 more
wiley   +1 more source

Correction: Two new species of the Entoloma quadratum-murrayi complex in Japan. [PDF]

PLoS One
PLOS ONE Staff.
europepmc   +1 more source

HP Newsletter Winter 2012 Download full pdf [PDF]

, 2012

core   +1 more source

Buch-Downloads

, 2004
openaire   +1 more source

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

Advanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li, Wentai Shangguan, Wenxue Huang, Jie Zhao, Yuexuan Zhu, Ming Xie, Yao Yu, Qishen Yang, Jun Zheng, Lin Yang, Qi Sun, Leqian Li, Xinhang Shi, Yongyuan Xiao, Hai Huang, Bisheng Cheng, Peng Wu   +16 more
wiley   +1 more source

Transdiagnostic-focused apps for depression and anxiety: a meta-analysis. [PDF]

NPJ Digit Med
Linardon J, Anderson C, Messer M, Liu C, Torous J.   +4 more
europepmc   +1 more source

Hörbuch-Download

, 2004
openaire   +1 more source

Glabridin‐Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity

Advanced Science, EarlyView.
Complex 6d could promote tumor immunogenicity by targeting thioredoxin reductase (TrxR) and remodel immunosuppressive microenvironment by the mitogen‐activated protein kinase (MAPK) pathway inhibition simultaneously. This study provides a novel approach to develop metal immunomodulatory agents by designing gold complexes incorporating natural products,
Zhaoran Wang, Meiyu Wang, Qiong Chen, Mengshi Wang, Fuwei Li, Lin Lv, Zhenfan Wen, Zhongren Xu, Yixia Yang, Chunyang Bi, Wukun Liu   +10 more
wiley   +1 more source

Japan-Medical Image Database (J-MID): Medical Big Data Supporting Data Science. [PDF]

Juntendo Med J
Akashi T, Kumamaru KK, Wada A, Hashimoto M, Hirata K, Hayakawa Y, Sano K, Kamagata K, Hagiwara A, Ikenouchi Y, Aoki S.   +10 more
europepmc   +1 more source

FemXpress: Systematic Analysis of X Chromosome Inactivation Heterogeneity in Female Single‐Cell RNA‐Seq Samples

Advanced Science, EarlyView.
FemXpress is a computational tool that leverages X‐linked single nucleotide polymorphisms (SNPs) to group cells by the origin of the inactivated X chromosome in female single‐cell RNA sequencing (scRNA‐Seq) data. It demonstrates strong performance on both simulated and real datasets without requiring parental genomic information, and can also identify ...
Xin Wang, Yingke Ma, Fan Li, Wentao Cui, Tianshi Pan, Siqi Wang, Sinan Ma, Qingtong Shan, Chao Liu, Yukai Wang, Ying Zhang, Yuanchun Zhou, Wei Li, Pengfei Wang, Qi Zhou, Guihai Feng   +15 more
wiley   +1 more source