Results 21 to 30 of about 11,753,787 (293)
Scale-free download network for publications
, 2004 The scale-free power-law behavior of the statistics of the download frequency of publications has been, for the first time, reported. The data of the download frequency of publications are taken from a well-constructed web page in the field of economic ...
Cai Xiang-Zhou +13 more
core +1 more source
Determinants of Downloads as Demand for Hybrid Journals
Liber Quarterly: The Journal of European Research LibrariesAlthough Big Deal contracts that provide access rights to all electronic journals published by the publisher initially gained favor with university libraries, some libraries have terminated these contracts owing to increased charges since the 2010s ...
Sumiko Asai
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
CompilerPhysical data storage using flash drives or local computer storage continues to be used for document archiving in database laboratories. Archived documents include laboratory inventory modules, practical course modules, practitioners' attendance cards ...
Prita Haryani +3 more
doaj +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Downloads legais versus ilegais: como aumentar a legalidade no consumo de música?
REAdUm grande problema da indústria fonográfica é lidar com os consumidores que fazem download de músicas pela internet de modo considerado ilegal sem pagar direitos autorais.
Bruno Canongia Baeta Alvim +2 more
doaj +1 more source