Results 131 to 140 of about 1,189,976 (248)
Advanced Science, EarlyView.Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu +7 more
wiley +1 more source
Darling Downs 20 chain map Sheet no. 183A [cartographic material].
, 1887 Cadastral map of the Darling Downs, Queensland.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.map-rm2016 ...
Queensland. Surveyor General's Office.
core
Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2
Advanced Science, EarlyView.Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang +15 more
wiley +1 more source
Advanced Science, EarlyView.The IgLec gene family generates both protein‐coding antiviral effectors and non‐coding transcripts. Upon viral infection, non‐coding transcripts are preferentially targeted by viral miR‐N48, thereby buffering protein‐coding isoforms from repression. Depletion of these decoy transcripts compromises antiviral defense, revealing a non‐coding RNA‐mediated ...
Ying Huang +5 more
wiley +1 more source
Down syndrome and consanguinity.
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013 Among the genetics disorders, Down syndrome (DS) is the major cause of mental retardation, congenital heart and intestinal disease. So far, no certain therapeutic method has been suggested for the treatment of this syndrome. The aim of the current survey was to investigate the frequency of parental consanguinity, maternal age in the patients with DS ...
Amir Akhavan Rezayat +6 more
openaire +2 more sources
Atypical localization of congenital triangular alopecia associated with Down's syndrome
Indian Journal of Dermatology, 2022 Kanade Shimada +6 more
doaj +1 more source
Amendments intended to be proposed by Mr. Downs, to the bill (H.R. 201) ...
A list of amendments regarding slavery intended to be proposed by Solomon W. Downs, Senator from Louisiana, to the bill (H.R.
United States. Congress (30th, 1st session : 1847-1848). Senate; Downs, Solomon W. (Solomon Weathersbee), 1801-1854; United States. Congress. House; United States. Congress. Senate
core
Advanced Science, EarlyView.GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko +5 more
wiley +1 more source
Study of congenital heart diseases amongst children with Down's syndrome
Journal of Clinical and Scientific Research, 2023 Mahmood Dhahir Al-Mendalawi
doaj +1 more source
Advanced Science, EarlyView.Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang +13 more
wiley +1 more source