STC2-mediated calcium homeostasis dysregulation in the osteosarcoma microenvironment: Insights from single-cell sequencing and machine learning. [PDF]
Yao K +6 more
europepmc +1 more source
AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee +21 more
wiley +1 more source
Loss of PRKACB facilitates metastasis of diffuse-type gastric cancer through RhoA signaling activation. [PDF]
Sun J +9 more
europepmc +1 more source
A Scalable Perovskite Platform With Multi‐State Photoresponsivity for In‐Sensor Saliency Detection
A scalable in‐sensor computing platform (32 × 32 array) with ultra‐low variability is developed by incorporating ferroelectric copolymers into halide perovskite thin films. These devices achieve 1000 programmable photoresponsivity states and high thermal reliability.
Xuechao Xing +10 more
wiley +1 more source
Role of microRNA-136 in <i>Helicobacter pylori</i>-induced early-stage gastric cancer: Mechanistic insights and future directions. [PDF]
Chen YX, Zhang YH, Mo SJ.
europepmc +1 more source
ABSTRACT Bone tissue regeneration is a complex physiological process dependent on the spatiotemporal coordination of immune cells and stem cells. Conventional research primarily elucidates the mechanism through which materials facilitate bone formation by initially modulating macrophages and subsequently encouraging the osteogenic differentiation of ...
Yang Lu +11 more
wiley +1 more source
Incretin Mimetics in Cancer and Cardiovascular Disease: JACC: CardioOncology State-of-the-Art Review. [PDF]
Leong D +6 more
europepmc +1 more source
Bioelectrical Interfaces Beyond Excitable Cells: Cancer, Aging, and Gene Expression Modulation
ABSTRACT The investigation of biological conductivity has evolved from its classical foundation based on ionic fluxes underpinning cardiac and neuronal excitability to a multifaceted regulator of cellular physiology. Traditional approaches for probing electrical events in living matter focused largely on action potentials recording.
Paolo Cadinu +14 more
wiley +1 more source
Abrine targets ERK to suppress EMT and lung metastasis model via MAPKs and Nrf2/Keap-1/HO-1 signaling. [PDF]
Shen Y +9 more
europepmc +1 more source
Mesenchymal stem cell derived extracellular vesicles (MSC‐EVs) are a promising therapeutic tool for regenerative medicine. However, the field lacks a reproducible high‐yield production method to answer the quantities needed for clinical translation.
Christophe Wong +7 more
wiley +1 more source

