An In Vitro Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration
Background. Diabetic retinopathy (DR) is a leading cause of blindness in working-age populations. Proper in vitro DR models are crucial for exploring pathophysiology and identifying novel therapeutic targets.
Qiyun Wang +7 more
doaj +1 more source
Aim: It is important to identify anti-cancer compounds that can inhibit specific molecular targets to eradicate androgen-receptor negative (ARneg), androgen-independent (AI) prostate cancer, which is an aggressive form of prostate cancer with limited ...
Vignesh Sivaganesh, Bela Peethambaran
doaj +1 more source
Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain
Activation of intravesical protease activated receptors-4 (PAR4) results in bladder pain through the release of urothelial macrophage migration inhibitory factor (MIF) and high mobility group box-1 (HMGB1). We aimed to identify HMGB1 downstream signaling
Shaojing Ye +5 more
doaj +1 more source
Low molecular weight fucoidan (LMWF) has been reported to have immunomodulation effects through the increase of the activation and function of macrophages.
Litong Liu +9 more
doaj +1 more source
Remotely sensed mid-channel bar dynamics in downstream of the Three Gorges Dam, China [PDF]
The downstream reach of the Three Gorges Dam (TGD) along the Yangtze River (1560 km) hosts numerous mid-channel bars (MCBs). MCBs dynamics are crucial to the river’s hydrological processes and local ecological function.
Shao, Guofan +4 more
core +1 more source
Ecology of common bully (Gobiomorphus cotidianus) in the Tarawera and Rangitaiki rivers: isolation by inland distance or anthropogenic discharge? [PDF]
Previous research has identified distinct genetic, life-history and reproductive differences between populations of common bully (Gobiomorphus cotidianus) upstream and downstream of a pulp and paper mill outfall on the Tarawera River in the Bay of Plenty,
Ahnelt H +11 more
core +2 more sources
European eel (Anguilla anguilla): prediction of spawner escapement from continental population parameters [PDF]
This paper describes the assessment of silver European eel (Anguilla anguilla) escapement based on a “sedentary” population fraction analysis in a 60-km2 watershed of northern Brittany (France).
Acou, Anthony +3 more
core +4 more sources
Towards a standardized characterization of the potentially migrating silver European eel (Anguilla anguilla L.) [PDF]
We defined a standardized method for discriminating candidate silver eels that may undergo catadromous migration in the following season from the sedentary fraction of a population.
Acou, Anthony +4 more
core +3 more sources
Spatial distribution of an eel population (Anguilla anguilla L.) in a small coastal catchments of northern Brittany (France). Consequences hydraulic works. [PDF]
The Frémur is a 60 km2 catchment of Brittany where many hydraulic works (dams, weirs, gauging structures, etc.) have reduced the recruitment by elvers and glass eels since at least 50 years.
Acou, Anthony +4 more
core +3 more sources
Migration pattern of silver eel (Anguilla anguilla, L.) in an obstructed river system. [PDF]
The downstream migration of European silver eels in the River Frémur was examined to determine the potential effects of the numerous migration barriers that exist on waterways in western France.
Acou +62 more
core +3 more sources

