Results 181 to 190 of about 3,733,624 (286)

Downstream of downstream processing – Integrated bioprocess development from upstream to downstream [PDF]

Chemie Ingenieur Technik, 2009
F. Grote, R. Ditz, J. Strube
openaire   +1 more source

A Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies. [PDF]

Biotechnol Bioeng
Carvalho M, Cruz A, Haringa C, Ottens M, Klijn M.   +4 more
europepmc   +1 more source

Determining buffer conditions for downstream processing of VLP-based recombinant hepatitis B surface antigen using multimodal resins in bind-elute and flow-through purification modes. [PDF]

Sci Rep, 2023
Goodarzi MM, Jalalirad R, Doroud D, Hozouri H, Aghasadeghi M, Paryan M.   +5 more
europepmc   +1 more source

Integrated Continuous Downstream Processing of Biopharmaceuticals

Biopharmaceuticals, of which monoclonal antibodies are a mainstay, have revolutionized healthcare by enabling treatments with high precision and efficacy.
Isaksson, Madelène
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Pilot-Scale Downstream Processing of Recombinant Influenza Virus Vectors Expressing <i>Brucella</i> spp. Antigens Using an Integrated Membrane-Chromatography Purification Platform. [PDF]

Vaccines (Basel)
Assanzhanova N, Sagymbayeva A, Shynybekova G, Shorayeva K, Ryskeldinova S, Mailybayeva A, Myrzakhmetov Y, Yamanova E, Sidikhov R, Almezhanova M, Zhaksylyk S, Absatova Z, Zhugunissov K, Chervyakova O, Akmyrzayev N.   +14 more
europepmc   +1 more source

Industrial Scale Manufacturing and Downstream Processing of PLGA-Based Nanomedicines Suitable for Fully Continuous Operation. [PDF]

Pharmaceutics, 2022
Operti MC, Bernhardt A, Sincari V, Jager E, Grimm S, Engel A, Hruby M, Figdor CG, Tagit O.   +8 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Current PAT Landscape in the Downstream Processing of Biopharmaceuticals. [PDF]

Anal Sci Adv
Sathiyapriyan P, Mukherjee S, Vogel T, Essen LO, Boerema D, Vey M, Kalina U.   +6 more
europepmc   +1 more source

In-line monitoring of surfactant clearance in viral vaccine downstream processing. [PDF]

Comput Struct Biotechnol J, 2021
Payne J, Cronin J, Haer M, Krouse J, Prosperi W, Drolet-Vives K, Lieve M, Soika M, Balmer M, Kirkitadze M.   +9 more
europepmc   +1 more source