Results 51 to 60 of about 3,733,624 (286)

Microbial production of scleroglucan and downstream processing

Frontiers in Microbiology, 2015
Synthetic petroleum-based polymers and natural plant polymers have the disadvantage of restricted sources, in addition to the non-biodegradability of the former ones.
Natalia Alejandra Castillo, Natalia Alejandra Castillo, Alejandra Leonor Valdez, Alejandra Leonor Valdez, Julia Ines Fariña, Julia Ines Fariña   +5 more
doaj   +1 more source

The Expression and Localization of N-Myc Downstream-Regulated Gene 1 in Human Trophoblasts [PDF]

, 2013
The protein N-Myc downstream-regulated gene 1 (NDRG1) is implicated in the regulation of cell proliferation, differentiation, and cellular stress response.
Shi, Xiao-Hua, Shi, XH, Jacob C. Larkin, Baosheng Chen, Xiao-Hua Shi (2286394), Larkin Jacob C., Larkin, Jacob C., Yoel Sadovsky, Baosheng Chen (294603), Larkin, JC, Chuang, Eric Y., Jacob C Larkin, Chen Baosheng, Sadovsky, Y, Shi Xiao-Hua, Chen, Baosheng, Sadovsky, Yoel, Sadovsky Yoel, Yoel Sadovsky (199874), Jacob C. Larkin (459267), Chen, B, Xiao-Hua Shi, Larkin, Jacob C   +22 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Emerging technologies for the integration and intensification of downstream bioprocesses [PDF]

, 2013
Downstream processing is currently the major bottleneck for bioproduct generation. In contrast to the advances in fermentation processes, the tools used for downstream processes have struggled to keep pace in the last 20 years. Purification bottlenecks
Azevedo, Ana M., Aires Barros, M. Raquel, D’Souza, Roy N., Kramberger, Petra, Carbajal, Maria Laura, Meyer, Ronald, Fernandez Lahore, Marcelo, Krajnc, Nika Lendero, Grasselli, Mariano   +8 more
core   +1 more source

Comparative Study of Response Surface Methodology, Artificial Neural Network and Genetic Algorithms for Optimization of Soybean Hydration

Food Technology and Biotechnology, 2010
The present investigation deals with the modelling and optimization of soybean hydration for facilitating soybean processing and it focuses on maximization of mass gain, water uptake and protein retention in the bean.
Tushar Gulati, Mainak Chakrabarti, Anshu Sing, Anshu Sing, Muralidhar Duvuuri, Rintu Banerjee   +5 more
doaj  

Membrane-Based Downstream Processing of Microbial Xylitol Production

International Journal of Technology, 2017
Xylitol is a sugar alcohol used as a sweetener in the food industry. Xylitol can be produced from D-xylose using a fermentation process, but it then needs to be separated from the other components of the fermentation broth (e.g., metabolic products ...
Ria Desiriani, Made Tri Ari Penia Kresnowati, I Gede Wenten   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Actinobacillus succinogenes in Bioelectrochemical Systems: Influence of Electric Potentials and Carbon Fabric Electrodes on Fermentation Performance

Microorganisms
The fermentation of Actinobacillus succinogenes in bioelectrochemical systems offers a promising approach to enhance biotechnological succinate production by shifting the redox balance towards succinate and simultaneously enabling CO2 utilization.
Julian Tix, Jan-Niklas Hengsbach, Joshua Bode, Fernando Pedraza, Julia Willer, Sei Jin Park, Kenneth F. Reardon, Roland Ulber, Nils Tippkötter   +8 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source