The Neuroprotective Effect of Doxycycline on Neurodegenerative Diseases
F. Santa-Cecília +3 more
semanticscholar +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre +2 more
wiley +1 more source
KLF18 is a necessary component of the DUX4-initiated transcriptional network and a candidate locus for phenotypic diversity. [PDF]
Hamm DC +6 more
europepmc +1 more source
PD‐L1‐Inhibitor‐Associated Hidradenitis Suppurativa
Journal of Cutaneous Pathology, EarlyView.
Annie Jin +2 more
wiley +1 more source
Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo +2 more
wiley +1 more source
Draft genome assemblies of doxycycline-resistant derivatives of <i>Bacillus cereus</i> strain ATCC14579. [PDF]
Harrison S +8 more
europepmc +1 more source
European S2k guidelines on management of autoimmune blistering diseases in children and adolescents
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda +31 more
wiley +1 more source
Core-shell microneedles Co-loaded with simvastatin and doxycycline for combined anti-infection and osteogenesis in diabetic periodontitis. [PDF]
Zhang S +6 more
europepmc +1 more source
Update of the EuroGuiDerm evidence‐based guideline for the treatment of acne—Short version
The 2025 EuroGuiDerm guideline update provides evidence‐based recommendations for acne management, addressing systemic antibiotics, systemic isotretinoin, hormonal therapies including spironolactone and contraceptives, and new topical agents. Key considerations include treatment duration, safety, pregnancy‐specific guidance and minimizing antibiotic ...
Alexander Nast +22 more
wiley +1 more source

