Results 171 to 180 of about 246,662 (243)

A Fentanyl‐Responsive Microneedle Patch for Harm Reduction

Advanced Science, EarlyView.
A fentanyl‐responsive microneedle patch is developed as a self‐regulating overdose intervention that releases naloxone upon detecting fentanyl. The system employs aptamer‐functionalized nanoparticles embedded in a swellable polymer matrix to enable rapid, on‐demand drug delivery through the skin.
Penghui Zhao, Zerui Zhou, Tyler Wolter, Huanqing Niu, Yuanzhi Bian, Chixia Tian, Chun Xu, Chenming Zhang, Juhong Chen, Matthew W. Buczynski, Wujin Sun   +10 more
wiley   +1 more source

Type‐II Dirac Fermions in Monolayer In2O: Interplay of Magnetotransport, Spin Hall Effect, and Superconductivity

Advanced Science, EarlyView.
First‐principles calculations reveal that monolayer In2O${\rm In}_2{\rm O}$ hosts type‐II Dirac fermions near the Fermi level, which split into Weyl points under spin‐orbit coupling. The material exhibits negative and giant magnetoresistance, a pronounced spin Hall effect, and phonon‐mediated superconductivity at 1.5 K, establishing it as a unique ...
Qing‐Bo Liu, De‐Ming Feng, Wen‐Neng Zhao, Yu‐Yang Zhao, Lun Xiong, Xing‐Yi Tan, Hua‐Hua Fu   +6 more
wiley   +1 more source

Efficacy and safety of sacubitril/valsartan in patients on peritoneal dialysis: a systematic review and meta-analysis. [PDF]

J Bras Nefrol
Silva CLD, Fonseca PEO, Calice-Silva V, Ponce D, Rocha PN, Guimarães MG.   +5 more
europepmc   +1 more source

Metal (n+1)p‐nd Orbital Hybridization and Excited‐State Metal–Ligand π‐Interactions Enable d10 Carbene‐Metal‐Amide TADF OLEDs with High Efficiency and Long Operational Lifetime

Advanced Science, EarlyView.
We elucidate the key roles of metal p‐d orbital hybridization, excited‐state metal–ligand π‐interactions, and structural rotation in TADF of d10 CMA complexes. Introducing electron‐withdrawing or π‐extended ligand substituents weakens excited‐state metal‐ligand π‐interactions and improves kTADF, but may compromise emitter stability in device operation.
Shuo Xu, Rui Tang, Qingyun Wan, Gang Cheng, Jun Yang, Chi‐Ming Che   +5 more
wiley   +1 more source

Resolving Isomeric Structures in Natural Complex Carbohydrates: A Comparative Study of SLIM and Cyclic Ion Mobility Platforms. [PDF]

Rapid Commun Mass Spectrom
Benazza R, Harrilal CP, Ibrahim YM, Fanuel M, Ropartz D, Rogniaux H.   +5 more
europepmc   +1 more source

Physics‐Informed Machine Learning for Sustainable Alloy Design: Toward a Recyclable Unified Q&P Steel

Advanced Science, EarlyView.
A physics‐informed property‐bridging framework links high‐throughput hardness screening to tensile performance in quenching and partitioning steels. By transferring metallurgically guided representations across properties, a single alloy composition is designed to achieve multiple strength grades through heat‐treatment tuning alone, offering a ...
Xiaolu Wei, Yong Li, Chenchong Wang, Lingyu Wang, Xiang Song, Keming Mao, Yu Zhang, Wei Xu   +7 more
wiley   +1 more source

A Non‐Canonical Core Transcriptional Regulatory Circuit Orchestrates Chromatin Reprogramming to Drive Osimertinib Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A non‐canonical core transcriptional regulatory circuit, composed of ID3, SMAD3, and NR2F2, drives Osimertinib resistance in non‐small cell lung cancer through super‐enhancer‐mediated activation of EPAS1, which couples neuroendocrine differentiation with ferroptosis evasion.
Aochu Liu, Zhenguo Liu, Lizhen Jiang, Andong Huang, Xinqing Lin, Xinyue Li, Bingyuan Liu, Shiwen Hu, Qiang Pan, Junjun Huang, Liyuan Yin, Liling Jiang, Wei Yi, Wenjun Mao, Yueyuan Zheng, Xianping Shi   +15 more
wiley   +1 more source

The Dysregulation Profile and Substance Use: Investigating Their Co-Variation From Adolescence to Emerging Adulthood. [PDF]

Emerg Adulthood
Cooper-Dubé TR, Shen A, Sukhawathanakul P.   +2 more
europepmc   +1 more source

Pressure‐Driven Phase Transition Unlocking Unique Eu2+ Luminescence in Li2SrSiO4 for Optical Sensing and White‐LEDs

Advanced Science, EarlyView.
This study demonstrates, for the first time, the use of a large‐format high‐pressure press to modify synthesized Li2SrSiO4:Eu2+,Cs+ phosphors after its preparation. The pressure treatment results in the formation of new materials with distinctive optical properties, opening pathways for the development of advanced LED devices and high‐performance ...
Przemysław Woźny, Peng Du, Teng Zheng, Junpeng Xue, Liang Peng, Shuailing Ma, Szymon Sobczak, Victor Lavín, Tian Cui, Marcin Runowski   +9 more
wiley   +1 more source