Results 171 to 180 of about 99,253,553 (299)

Cost and clinical impact of a nonmedical DPP-4 inhibitor switch in patients with diabetes. [PDF]

open access: yesJ Manag Care Spec Pharm, 2021
Kheloussi S   +4 more
europepmc   +1 more source

TcFur1, a furin 1 ortholog in Tribolium castaneum, regulates reproduction and carbohydrate metabolism without affecting lipid homeostasis

open access: yesInsect Molecular Biology, EarlyView.
TcFur1, a furin 1 ortholog in Tribolium castaneum, is highly expressed in pupae and declines in adults. TcFur1 knockdown reduces oviposition but does not alter triacylglycerol levels or total lipase activity. TcFur1 knockdown increases circulating trehalose and decreases expression of insulin‐like peptides and the AKH receptor.
Julia Sanches‐Almeida   +2 more
wiley   +1 more source

Role of glucagon in metabolic diseases

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Currently, diabetes is defined as “a chronic hyperglycemic state resulting from the absolute or relative insufficiency of insulin action,” emphasizing its characterization as an insulin‐related disease. However, glucagon dysregulation should also play a critical role in the pathophysiology of type 2 diabetes.
Tadahiro Kitamura   +2 more
wiley   +1 more source

Diabetes attenuates weight reduction‐mediated liver fibrosis regression in persons with morbid obesity

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims Weight loss by laparoscopic sleeve gastrectomy (LSG) compared to medical weight loss (low‐calorie diet: LCD) ameliorates diabetes and metabolic dysfunction‐associated steatotic liver disease (MASLD). We aimed to evaluate changes in liver pathology 1‐year after LSG and their associations with metabolic factors in Japanese participants with
Daiki Matsubara   +11 more
wiley   +1 more source

Parasympathetic dysfunction assessed by deep‐breathing CVR‐R is associated with early discontinuation of oral semaglutide in type 2 diabetes: A multicenter retrospective study

open access: yesJournal of Diabetes Investigation, EarlyView.
Lower CVR‐R during deep breathing (CVR‐R_DB), a marker of parasympathetic function, was associated with early discontinuation of oral semaglutide due to nausea and/or vomiting in patients with type 2 diabetes. CVR‐R_DB may support risk stratification at treatment initiation.
Kazuma Ogiso   +5 more
wiley   +1 more source

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