Results 131 to 140 of about 13,289,433 (300)

Sitagliptin a DPP 4 Inhibitor

International Journal for Research Trends and Innovation, 2023
Purvita Laxman waghmodey, Mayur Rajkumar Raut, Manorama Namdev Naiknaware   +2 more
openaire   +1 more source

Lactobacilli possess inhibitory activity against dipeptidyl peptidase-4 (DPP-4)

, 2015
Dipeptidyl peptidase 4 (DPP-4) enzymatically inactivates incretin hormones, and DPP-4 inhibitor drugs are clinically approved therapies for type 2 diabetes.
Panwar, Harsh, Calderwood, Danielle, Green, Brian D., Grover, Sunita, Grant, Irene R.; id_orcid   +4 more
core   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Funnel plot for mean difference (MD) in the change in HbA1c (DPP-4 inhibitor vs. placebo or no treatment).

, 2014
Funnel plot for mean difference (MD) in the change in HbA1c (DPP-4 inhibitor vs. placebo or no treatment).
Dongsheng Cheng (652883), Xiaoxia Wang (14667), Junhui Li (304434), Yumei Liu (286628), Yuqiang Chen (652884), Niansong Wang (304438), Yang Fei (504329)   +6 more
core   +1 more source

Clinical Impact of Target‐Mediated Drug Disposition of Small Molecules with Focus on Early Phase I Study Designs

Clinical Pharmacology &Therapeutics, EarlyView.
Francesca Tessaro, Neil John Parrott, Matthias B Wittwer, Franziska Schaedeli Stark, Andrés Olivares‐Morales, Michael Derks, Stefan Sturm   +6 more
wiley   +1 more source

Bromelain as the enzyme of the future: A global bibliometric mapping of its applications and emerging trends

Journal of the Science of Food and Agriculture, EarlyView.
Abstract INTRODUCTION Bromelain, a complex mixture of proteolytic enzymes primarily extracted from plants of the Bromeliaceae family, has gained prominence because of its broad industrial applicability, particularly in the food, pharmaceutical and cosmetic sectors.
Genésio José da Silva Neto, Tonny Cley Campos Leite, Mônica Tejo Cavalcanti, Geany Targino Sousa Pedrosa, Rerisson do Nascimento Alves, Amanda Reges de Sena, Mônica Correia Gonçalves   +6 more
wiley   +1 more source

Saxagliptin: a new DPP-4 inhibitor for the treatment of type 2 diabetes mellitus

, 2009
Type 2 diabetes mellitus (T2DM) is a global epidemic with increasing impact on individuals and healthcare providers. Available treatments (such as metformin, sulfonylureas, glitazones, and insulin) have proven unsatisfactory in producing a long-lasting ...
Piya, Milan K, Piya, Milan, Piya, Milan K. (R19111), Barnett, Anthony, R. Keith Campbell, Barnett, Anthony H., Tahrani, Abd A., Tahrani, Abd; id_orcid, Joshua J. Neumiller, Barnett, Anthony H, Tahrani, Abd A   +10 more
core   +1 more source

Correlations Among Glycemia and Glucose Variability, Thyroid Hormones, and Albuminuria in Patients With Type 2 Diabetes Mellitus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hyperglycemia, glucose fluctuations, and thyroid dysfunction contribute to the progression of diabetic nephropathy. This study aimed to investigate the associations of glycemia, glucose variability, and thyroid hormones with albuminuria in patients with type 2 diabetes mellitus (T2DM). In total, 451 T2DM patients were included.
Na Luo, Shang‐Yong Feng, Hui Chen, Dun‐Min She, Yan Liu, Ying Li, Cai‐Feng Yan, Zhen‐Wen Zhang, Jing Chen, Xiao‐Li Cai, Gao‐Yu Zhao, Hui Yu, Yan Wang   +12 more
wiley   +1 more source

Alogliptin benzoate for management of type 2 diabetes

Vascular Health and Risk Management, 2015
Yoshifumi Saisho Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan Abstract: Dipeptidyl peptidase-4 (DPP-4) inhibitors, a new class of oral hypoglycemic agents, augment glucose-dependent insulin secretion and suppress ...
Saisho Y
doaj  

Assessing Extracellular Vesicle Proteins as Predictive Biomarkers for Developing Type 1 Diabetes

PROTEOMICS, EarlyView.
ABSTRACT Plasma extracellular vesicles (EVs) are considered excellent sources for biomarker discovery since they carry signatures of their cellular origin and disease processes. In this paper, we evaluate the potential of plasma EV proteomics analysis for identifying predictive biomarkers of developing type 1 diabetes (T1D), which results from ...
Panshak P. Dakup, Lisa M. Bramer, Athena Schepmoes, Ivo Diaz Ludovico, Javier Flores, Raghavendra G. Mirmira, Bobbie‐Jo M. Webb‐Robertson, Thomas O. Metz, Emily K. Sims, Ernesto S. Nakayasu   +9 more
wiley   +1 more source