Results 181 to 190 of about 24,589 (267)

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway, Cinzia Dello Russo, Nicholas Bass, Elvira Bramon, Helen Cross, Natalie Curley, Sarah Curran, Helen Davies, Jana De Villiers, William Evans, Bernhard Frank, Alice Groves, Judith Hayward, Jon Higham, Dyfrig A. Hughes, Shwe Sin Kyaw, Anthony G. Marson, Ailsa McLellan, Seth Mensah, Francis O'Neill, Jane Sargison, Sanjay M. Sisodiya, Jill Swan, Joanna M. Zakrewska, Munir Pirmohamed   +24 more
wiley   +1 more source

Immunotherapy-based regimens for patients with EGFR-mutated non-small cell lung cancer who progressed on EGFR-TKI therapy. [PDF]

J Immunother Cancer
Qin BD, Jiao XD, Yuan LY, Wu Y, Ling Y, Zang YS.   +5 more
europepmc   +1 more source

Infusion rate adjustment in enzyme replacement therapy with pabinafusp alfa for mucopolysaccharidosis II

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Enzyme replacement therapy (ERT) for mucopolysaccharidosis II (MPS II) requires long‐term, weekly intravenous infusions often lasting over 3 h each time, which can burden paediatric patients and caregivers and negatively affect their quality of life and treatment compliance.
Kimitoshi Nakamura, Norio Sakai, Hideaki Hirai, Naoko Takasao, Ryo Ibaraki, Tatsuyoshi Yamamoto, Yuji Sato   +6 more
wiley   +1 more source

Fossorial Form of Water Voles Select and Overexploit High-Quality Habitats, Hindering Future Colonizations Evidence From Drone-Based Monitoring of Dandelion-Vole Interactions in Mountain Meadows. [PDF]

Ecol Evol
Buronfosse M, Lisse H, Couval G, Levret A, Gillet F, Lattard V, Pinot A.   +6 more
europepmc   +1 more source

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

Brain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye, Fei Peng, Chao Pan, Ping Zhang, Xuewei Xie, Zixiao Li, Yingxin Tang, Danyang Chen, Yuanwei Li, Jiawen Wu, Zao Han, Qing Dai, Quansheng Gu, Jizong Zhao, Zhouping Tang   +14 more
wiley   +1 more source

<i>Dentipellicula hainanensis</i> (Hericiaceae, Agaricomycetes) and <i>Phylloporia rigida</i> (Hymenochaetaceae, Agaricomycetes), two new species of wood-inhabiting fungi from Hainan Province, South China. [PDF]

MycoKeys
Song CG, Gao JT, Yang BW, Jia ZF.
europepmc   +1 more source

Landscape of Immune Remodeling and NAP1L1‐Driven Epithelial Reprogramming in Gastric Cancer Metastasis

Chronic Diseases and Translational Medicine, EarlyView.
High‐resolution single‐cell atlas of normal gastric tissue, primary gastric cancer, and metastatic lesions. (A) Schematic diagram of experimental design. (B) Bar plot for qualified cell numbers in each lesion. (C) Cells annotation by canon markers for all cells. (D) Bubble chart for canon marker genes for each cell subtype.
Min Sun, Yuanzhi Wang, Yuqing Zhang, Xiaojuan Wang   +3 more
wiley   +1 more source

Genetic Association in Immunoglobulin G4-Related Disease: A Systematic Review.

Int Arch Allergy Immunol
Hei Lai KK, Tang T, Tsing Ho AY, Sin Tam PO, Chen LJ, Yung Tham CC, Pang CP, Lung Chong KK.   +7 more
europepmc   +1 more source

Physical and Statistical Pattern of the Thiva (Greece) 2020-2022 Seismic Swarm. [PDF]

Entropy (Basel)
Vallianatos F, Sardeli E, Pavlou K, Karakonstantis A.   +3 more
europepmc   +1 more source

Electronic Resonance Network Stabilized Crystal Structure in High‐Nickel Cathodes for Lithium‐Ion Batteries

Carbon Energy, EarlyView.
Transition metal (TM) ions with empty eg orbitals induce single‐electron delocalization in Ni3+ to form the resonance structure of Ni─OO─TM through the high‐entropy effect. High‐nickel cathode materials with electron resonance structure have the advantages of improving thermodynamic stability, suppressing phase transitions, and mitigating lattice ...
Yi Li, Qinwen Cui, Jinpeng Li, Xingyu Li, Liang Yin, Erhong Song, Youwei Wang, Xiaolin Zhao, Jianjun Liu   +8 more
wiley   +1 more source