Results 81 to 90 of about 1,218,700 (283)

Antiviral regulator TRIM25 as a prognostic marker of better survival in Merkel cell carcinoma: Association with MCPyV status

International Journal of Cancer, EarlyView.
What's New? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt, Sami Kilpinen, Johanna Arola, Benjamin Z. Sundqvist, Tom Böhling, Leif C. Andersson, Harri Sihto   +6 more
wiley   +1 more source

Conocimientos, actitudes y prácticas con relación al método madre canguro del personal de salud que labora en la unidad pediátrica en centros de atención de segundo nivel de Santiago de los Caballeros, República Dominicana en el periodo abril-junio 2024

Ciencia y Salud
El Método Madre Canguro es una técnica de contacto piel con piel entre madre e hijo que favorece el desarrollo fisiológico, cardiopulmonar y neurológico de los recién nacidos.
Brandon Anthony Sánchez Rodríguez, Janett Ortiz Rivera, Alma Encarnación Vasquez, Isi Ortiz, Evangelina Altagracia Mercedes Hernández Gómez   +4 more
doaj   +1 more source

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

iMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji, Haochen Li, Qi Wang, Xiaojuan Wang, Jiawei Zhang, Ying Xiao, Huan Li, Hao Liu, Tanqing Long, Boyang Wu, Hao Chen, Haoming Xia, Xinquan Liu, Chuanrui Xu, Yibo Gao, Bingjun Tang, Juan Liu, Shizhong Yang, Jiahong Dong   +18 more
wiley   +1 more source

A large‐scale single‐cell transcriptomic atlas indicates the immune panorama of influenza A infection

iMeta, EarlyView.
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang, Shuzi Liu, Laurence Don Wai Luu, Yongzhi Zhai, Chenliang Zhu, Zhaomin Feng, Yao Tan, Linglong Wan, Jie Wang, Juan Zhou, Jing Wang, Lixin Xie, Quanyi Wang, Fei Xie   +13 more
wiley   +1 more source

Is catheterization via distal transradial access feasible in children? From vessel diameter perspective

Frontiers in Cardiovascular Medicine
BackgroundDistal radial artery (DRA) access is an infrequent alternative access for pediatric catheterization. The feasibility of using the DRA for arterial catheterization in children depends on the vessel's size.ObjectivesThis study aims to provide a ...
Yidong Zhao, Tao Chen, Ling Yang, Wenjie Mao, Yu Wan, Liwen Zhang, Heng Ding, Gaojun Cai, Zhiying Huang   +8 more
doaj   +1 more source

Expanding the Phenotype of TAB2‐Related Syndrome: The First Case With Cleft Palate and Insights Into Palatal Development

American Journal of Medical Genetics Part A, EarlyView.
Alberto De Rosa, Silvia Kalantari, Marta Carboni, Antonella Casella, Elisa Giorgio, Antonia Apicella, Alessia Claudia Codazzi, Fabio Sirchia   +7 more
wiley   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Distance and mass of pulsating stars from multicolour photometry and atmospheric models

, 2003
For determining distance and mass of pulsating stars a new, purely photometric method is described in which radial velocity observations are not needed. The method is compared with the Baade-Wesselink method. As an example the RR Lyrae variable SU Dra is
Baker, Barcza, Barnes, Baschek, Bessell, Buonaura, Castelli, Code, Cohen, Fernley, Gautschy, Gratton, Gratton, Hanbury Brown, Jones, Kurucz, Liu, Liu, Oke, S. Barcza, Sabbey, Siegel, Tüg   +22 more
core   +1 more source

Dra. Bertha Bouroncle

Anales de la Facultad de Medicina, 2014
Editorial
openaire   +5 more sources

Indirubin and Retinoic Acid Show Binding Affinity to Monocyte Biomarker CSF3R in Parkinson's Disease

Journal of Clinical Laboratory Analysis, EarlyView.
Through single‐cell RNA‐sequencing and high‐dimensional weighted gene co‐expression network analysis, two monocyte‐related biomarkers (CSF3R, IFITM3) were identified in the peripheral blood of Parkinson's disease. Molecular docking revealed two targeted drugs (Indirubin and Retinoic acid).
Zhiwei Bao, Shao Zhi, Mao Jie
wiley   +1 more source