Results 21 to 30 of about 2,823 (196)

Two residues determine nicotinic acetylcholine receptor requirement for RIC-3. [PDF]

Protein Sci, 2023
Abstract Nicotinic acetylcholine receptors (N‐AChRs) mediate fast synaptic signaling and are members of the pentameric ligand‐gated ion channel (pLGIC) family. They rely on a network of accessory proteins in vivo for correct formation and transport to the cell surface.
Noonan JD, Beech RN.
europepmc   +2 more sources

Human infection with an unknown species of Dracunculus in Vietnam

International Journal of Infectious Diseases, 2021
Guinea worm (GW) disease, caused by Dracunculus medinensis, is an almost eradicated waterborne zoonotic disease. The World Health Organization (WHO) currently lists GW as endemic in only five African countries.
Pham Ngoc Thach, H. Rogier van Doorn, Henry S. Bishop, Mark S. Fox, Sarah G.H. Sapp, Vitaliano A. Cama, Le Van Duyet   +6 more
doaj   +1 more source

Neuroimmune Pain and Its Manipulation by Pathogens. [PDF]

Evol Appl
ABSTRACT Recent studies highlight extensive crosstalk that exists between sensory neurons responsible for pain and the immune system. Cutaneous pain neurons detect harmful microbes, recruit immune cells, and produce anticipatory immunity in nearby tissues. These complementary systems generally protect hosts from infections.
Lozo KW, Aktipis A, Alcock J.
europepmc   +2 more sources

Susceptibility of anurans, lizards, and fish to infection with Dracunculus species larvae and implications for their roles as paratenic hosts

Scientific Reports, 2021
Dracunculus spp. are parasitic nematodes that infect numerous species of mammals and reptiles. The life cycles of Dracunculus species are complex, and unknowns remain regarding the role of paratenic and transport hosts in transmission to definitive hosts.
Erin K. Box, Michael J. Yabsley, Kayla B. Garrett, Alec T. Thompson, Seth T. Wyckoff, Christopher A. Cleveland   +5 more
doaj   +1 more source

Copepod consumption by amphibians and fish with implications for transmission of Dracunculus species

International Journal for Parasitology: Parasites and Wildlife, 2021
Parasitic nematodes in the genus Dracunculus have a complex life cycle that requires more than one host species in both aquatic and terrestrial habitats.
Erin K. Box, Christopher A. Cleveland, Kayla B. Garrett, Ryan K. Grunert, Katherine Hutchins, Ania A. Majewska, Alec T. Thompson, Seth T. Wyckoff, Coles Ehlers, Michael J. Yabsley   +9 more
doaj   +1 more source

Two cases of cystic echinococcosis reported from al‐Andalus cemeteries (southern Iberia): Insights into zoonotic diseases in Islamic Medieval Europe

International Journal of Osteoarchaeology, Volume 33, Issue 5, Page 910-919, September/October 2023., 2023
Abstract The identification of a calcified hydatid cyst in the bioarcheological record is key to the diagnosis of cystic echinococcosis (i.e., hydatid disease), a parasitic infection caused by the tapeworm Echinococcus granulosus. This zoonosis can be linked to human–canid interactions, given the reproductive cycle of the parasite (from canids to ...
Ramón López‐Gijón, Salvatore Duras, Rosa Maroto‐Benavides, Luis A. Mena‐Sánchez, Edgard Camarós, Sylvia Jiménez‐Brobeil   +5 more
wiley   +1 more source

The impact of AlphaFold Protein Structure Database on the fields of life sciences

PROTEOMICS, Volume 23, Issue 17, September 2023., 2023
Abstract Arguably, 2020 was the year of high‐accuracy protein structure predictions, with AlphaFold 2.0 achieving previously unseen accuracy in the Critical Assessment of Protein Structure Prediction (CASP). In 2021, DeepMind and EMBL‐EBI developed the AlphaFold Protein Structure Database to make an unprecedented number of reliable protein structure ...
Mihaly Varadi, Sameer Velankar
wiley   +1 more source

Spatial and temporal dynamics of space use by free‐ranging domestic dogs Canis familiaris in rural Africa

Ecological Applications, Volume 31, Issue 5, July 2021., 2021
Abstract Variation in the spatial ecology of animals influences the transmission of infections and so understanding host behavior can improve the control of diseases. Despite the global distribution of free‐ranging domestic dogs Canis familiaris and their role as reservoirs for zoonotic diseases, little is known about the dynamics of their space use ...
Jared K. Wilson‐Aggarwal, Cecily E. D. Goodwin, Tchonfienet Moundai, Metinou K. Sidouin, George J. F. Swan, Monique Léchenne, Robbie A. McDonald   +6 more
wiley   +1 more source

Ecology of domestic dogs (Canis familiaris) as a host for Guinea worm (Dracunculus medinensis) infection in Ethiopia

Transboundary and Emerging Diseases, Volume 68, Issue 2, Page 531-542, March 2021., 2021
Abstract The global programme for the eradication of Guinea worm disease, caused by the parasitic nematode Dracunculus medinensis, has been successful in driving down human cases, but infections in non‐human animals, particularly domestic dogs (Canis familiaris), now present a major obstacle to further progress. Dog infections have mainly been found in
Jared K. Wilson‐Aggarwal, Cecily E. D. Goodwin, George J. F. Swan, Helen Fielding, Zerihun Tadesse, Desalegn Getahun, Anyaro Odiel, Alamo Adam, Harry H. Marshall, Jessica Bryant, James A. Zingeser, Robbie A. McDonald   +11 more
wiley   +1 more source

How epidemics end

Centaurus, Volume 63, Issue 1, Page 210-224, February 2021., 2021
Abstract As COVID‐19 drags on and new vaccines promise widespread immunity, the world's attention has turned to predicting how the present pandemic will end. How do societies know when an epidemic is over and normal life can resume? What criteria and markers indicate such an end?
Erica Charters, Kristin Heitman
wiley   +1 more source