Results 101 to 110 of about 3,138,084 (331)

Legal enforcement of encouragement in local government for employees: essence, problems, and perspectives

Наукові записки НаУКМА: Юридичні науки, 2018
The article researches problems and perspectives of the legal enforcement of local self-government workers encouragement. Problems connected with the insufficient legal regulation of encouragement, in comparison with disciplinary rules, are considered ...
Petro Mozolevskyi
doaj   +1 more source

New Rules for Letters of Credit: Time to Update the UCP 600 [PDF]

, 2017
This article addresses the need for a revision of the UCP 600, international rules governing letters of credit. It identifies key articles that need amendments and is the first legal article to draft new provisions for the potential ?UCP 700?.
Antoniou, Anna Mari
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Quadro comum de referência: abandono da tradiçâo jurídica européia em nome da europeizacâo do Direito? [PDF]

, 2008
[Abstract] This article is about the Draft Common Frame of Reference, whose objective is providing a common regulation for the European Private Law, especially for the Law of Obligations.
Geraldes Ferreira, Vivianne
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

The normative significance of the valuation report in light of the resolution on disposing of real estate under a “premises in exchange for land” settlement

Studia Prawnicze KUL
With effect from 1 April 2021, the Act of 16 December 2020 on Disposing of Real Estate under a “Premises in exchange for Land” Settlement entered into force.
Szymon Słotwiński
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Accounting for Revaluation of Property, Plant and Equipment in 2017 and 2020: New in the Draft Federal Accounting Standard “Property, Plant and Equipment”

Учёт. Анализ. Аудит, 2019
Introduction, Purpose. The article deals with the accounting for revaluation of property, plant and equipment. There are two accounting procedures for that: the current one running in 2017, and the one to be introduced in 2020.
Aleksei Evgen’evich Ivanov, Ol’ga Gennad’evna Nikitina   +1 more
doaj   +1 more source

THE PROFESSIONALIZATION OF ETHICS [PDF]

, 2005
This Article looks at the importance of teaching law graduates to be ethical lawyers. The author hypothesizes that the current versions of the ethical rules and the structure of law firms have the potential to encourage the professionalization of ethics ...
Raymond, Margaret
core   +1 more source