Results 111 to 120 of about 474,588 (344)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Technical Note TN 2.4. Fuel sampling, tree ignition and burning tests in ADAI facilities [PDF]

open access: yes, 2019
In this document, the followed methodology to characterize several natural fuels (trees of Cupressus arizonica, Cupressocyparis leylandii, Prunus laurocerasus and Thuja occidentalis) is presented.
Agueda Costafreda, Alba   +3 more
core   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas   +18 more
wiley   +1 more source

Experimental and Numerical Simulations Predictions Comparison of Power and Efficiency in Hydraulic Turbine

open access: yesModelling and Simulation in Engineering, 2011
On-site power and mass flow rate measurements were conducted in a hydroelectric power plant (Mexico). Mass flow rate was obtained using Gibson's water hammer-based method.
Laura Castro   +3 more
doaj   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen   +18 more
wiley   +1 more source

Influence of runner blade number on hydraulic performance and flow control in draft tube of Francis turbine

open access: yesAdvances in Mechanical Engineering
As a widely used core component of hydropower generation, the stable and safe operation of the Francis turbine plays a very important role in engineering applications.
Jiahao Lu, Chenhan Su, Ran Tao
doaj   +1 more source

DC Circuit Powered by Orbital Motion: Magnetic Interactions in Compact Object Binaries and Exoplanetary Systems

open access: yes, 2012
The unipolar induction DC circuit model, originally developed by Goldreich & Lynden-Bell for the Jupiter-Io system, has been applied to different types of binary systems in recent years.
Lai, Dong
core   +1 more source

Characterization of The Rotating Vortex Rope Pressure Oscillations in a Kaplan Model Turbine Draft Tube

open access: diamond, 2023
Shahab Shiraghaee   +3 more
openalex   +1 more source

Home - About - Disclaimer - Privacy