Results 301 to 310 of about 669,071 (359)

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

open access: yesAdvanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li   +11 more
wiley   +1 more source

Harnessing the Immunomodulation of UV‐Exposed Keratinocyte Extracellular Vesicles for Inflammatory Disorder Treatment

open access: yesAdvanced Science, EarlyView.
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu   +16 more
wiley   +1 more source

Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment

open access: yesAdvanced Science, EarlyView.
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu   +18 more
wiley   +1 more source

Pleural drainage systems [PDF]

open access: possibleAnaesthesia, 1993
SummaryThe physics and the physiological principles of pleural or chest drainage systems are reviewed. The clinical management and complications of pleural drainage are summarised.
M. O'brien, Peter Kam, A. C. Kam
openaire   +2 more sources

Lymphoma of the nasolacrimal drainage system

Otolaryngology - Head and Neck Surgery, 1994
1. Primary lymphomas of the nasolacrimal system are rare. 2. Workup for suspected lesions should include careful history and physical examination, appropriate radiographic imaging including CT scanning, and adequate tissue biopsy. 3. Isolated lesions of the diffuse large cell subtype have a favorable prognosis with standard treatment modalities of ...
David S. Bardenstein   +2 more
openaire   +3 more sources

Drainage Systems for Condensation

Journal of Engineering for Power, 1974
Efficient condensing surfaces are highly desirable in the design of solar sea power plants utilizing the ocean temperature difference. This paper examines a number of surface designs and presents a convenient method for optimizing the design. In particular, the various parameters of a Gregorig surface are optimized.
Clarence Zener, A. Lavi
openaire   +2 more sources

Glans condom drainage system

Urology, 1978
A form-fitting glans condom has been developed for use in small uncircumcised males with neurogenic bladders to avoid the problems inherent with diapers. The method to make the glans condom and early successful use in 19 of 33 patients are noted.
G. Cochrane   +3 more
openaire   +3 more sources

Reconstruction of the Lacrimal Drainage System

Archives of Otolaryngology - Head and Neck Surgery, 1984
The lacrimal drainage system is both an anatomic and a physiologic system. Anatomic abnormalities may be a result of congenital defects, infection, trauma, or tumors. The physiologic action of the eyelids, if altered, will affect the tear flow as well as disturb the lacrimal pump. Physiologic and anatomic abnormalities may be defined using the Schirmer,
G. Richard Holt, Jean Edwards Holt
openaire   +3 more sources

Diseases of the lacrimal drainage system

Current Opinion in Ophthalmology, 2001
We will refer to lacrimal system pathologies involving the outflow pathways, as well as to the recent advances in the management of canalicular and lacrimonasal duct anomalies, including modifications to dacrycystorhinostomy technique, treatment for congenital obstructions, and lacrimal intubations.
Daniel Weil   +2 more
openaire   +3 more sources

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