Results 31 to 40 of about 729,511 (308)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Antecedents of Service Innovative Behavior: The Role of Spiritual Leadership and Workplace Spirituality

Organizacija, 2021
Background: Managers in labor-intensive industries are facing challenges on how to encourage innovation, as services are mostly offered by employees and not machines.
Alfarajat Hebah Suliman, Emeagwali Okechukwu Lawrence   +1 more
doaj   +1 more source

The Drawing of an Opera Theatre for Boito's Competition (1939)

, 2020
In 1938/39, the Accademia delle Belle Arti di Brera published the competition Camillo Boito entitled Project for a theatre to be used for performances of lyrical art. A group of students, G. Belloni, A. Fiocchi, A. Magnaghi-Delfino, M. Terzaghi, from the Regio Politecnico di Milano attended to the contest and won the first prize.
Alessandra Capanna, Paola Magnaghi-Delfino, Giampiero Mele, Tullia Norando   +3 more
openaire   +2 more sources

Small cities for a small country: Sustaining the cultural renaissance? [PDF]

, 2006
Copyright @ 2006 RoutledgeThis chapter explores the implications for smaller cities of adopting culture-led regeneration strategies. It is suggested that there is a divergence between cultural planning for long term sustainable urban cultural ...
Evans, G, Foord, J
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Investigation of persuasive system design predictors of competitive behavior in fitness application: A mixed-method approach

Digital Health, 2019
Fitness applications aimed at behavior change are becoming increasingly popular due to the global prevalence of sedentary lifestyles and physical inactivity, causing countless non-communicable diseases.
Kiemute Oyibo, Julita Vassileva
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Employee Competitive Attitude and Competitive Behavior Promote Job-Crafting and Performance: A Two-Component Dynamic Model

Frontiers in Psychology, 2018
While competition has become increasingly fierce in organizations and in the broader market, the research on competition at an individual level is limited. Most existing research focuses on trait competitiveness.
Haifeng Wang, Lei Wang, Chunquan Liu
doaj   +1 more source

Logics of Action, Globalization, and Employment Relations Change in China, India, Malaysia, and the Philippines [PDF]

, 2002
A logic of action framework is developed in order to conceptualize and understand the impact of globalization on employment relations, as well as to predict the future trajectory of employment relations.
Frenkel, Stephen, Kuruvilla, Sarosh
core   +2 more sources