Results 61 to 70 of about 287,372 (301)

Measuring Knowledge. Notations, Words, Drawings, Projections, and Numbers

open access: yesDiségno, 2020
Humans have communicated with each other since they became such. Undoubtedly, the fact that we have developed symbolic systems to communicate should account for such a difference.
Carlos L. Marcos, Michael Swisher
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Pictorial maps and maps with drawings

open access: yesGeodesy and Cartography, 2012
Cartography can be traced back to drawings of an area. Pictorial maps and map drawing do not lose their artistic appeal despite the standards of the present day cartography.
Romualdas Girkus   +1 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

[Hauberg Technical Ink Drawings BOH 1534]

open access: yes, 2005
Seven ink drawings on one board. Detailed drawings of cellular cross sections, a mosquito, and other biology studies. Brown tape surrounds matboard mounting.mastication grazing psalterium pylorus abomasum reticulum rumen Antennae GenitaliaTiff file ...
Father Edward Catich
core   +1 more source

Understanding Pre-Service Teachers’ Perceptions of the Ideal Learning Environment for Mathematical Activities Through Drawings

open access: yesBehavioral Sciences
Mathematical activities, which have the potential to engage students cognitively, are an essential component of modern educational approaches. The design of learning environments that facilitate the full realization of the potential of mathematical ...
Tuğba Yulet Yılmaz, Mustafa Gök
doaj   +1 more source

A Psychometric Study of the Kinetic-House-Tree-Person Scoring System for People with Psychiatric Disorders in Taiwan

open access: yesHong Kong Journal of Occupational Therapy, 2014
Objective/Background: The Kinetic-House-Tree-Person (KHTP) drawing test is widely used by psychiatric occupational therapists in Taiwan; however, very little support has been provided through studies examining its psychometric properties.
Chih-Ying Li   +5 more
doaj   +1 more source

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